Results 51 to 60 of about 9,348 (281)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Targeted photoimmunotherapy for cancer

Biomolecular Concepts, 2022
Photodynamic therapy (PDT) is a clinically approved procedure that can exert a curative action against malignant cells. The treatment implies the administration of a photoactive molecular species that, upon absorption of visible or near infrared light ...
Mussini Andrea, Uriati Eleonora, Bianchini Paolo, Diaspro Alberto, Cavanna Luigi, Abbruzzetti Stefania, Viappiani Cristiano   +6 more
doaj   +1 more source

Recent Advances of Photoactive Near-Infrared Carbon Dots in Cancer Photodynamic Therapy

Pharmaceutics, 2023
Photodynamic therapy (PDT) is a treatment that employs exogenously produced reactive oxygen species (ROS) to kill cancer cells. ROS are generated from the interaction of excited-state photosensitizers (PSs) or photosensitizing agents with molecular ...
Jinxing Song, Xiaobo Gao, Mei Yang, Weiju Hao, Ding-Kun Ji   +4 more
doaj   +1 more source

Genetically Encoded Photosensitizers as Light-Triggered Antimicrobial Agents [PDF]

International Journal of Molecular Sciences, 2019
Diseases caused by multi-drug resistant pathogens have become a global concern. Therefore, new approaches suitable for treating these bacteria are urgently needed. In this study, we analyzed genetically encoded photosensitizers (PS) related to the green fluorescent protein (GFP) or light-oxygen-voltage (LOV) photoreceptors for their exogenous ...
Fabienne Hilgers, Nora Lisa Bitzenhofer, Yannic Ackermann, Alina Burmeister, Alexander Grünberger, Karl-Erich Jaeger, Thomas Drepper   +6 more
openaire   +4 more sources

Phase Engineering of Atomically Precise Nanoclusters (APNCs) of Gold and Beyond

Advanced Materials, EarlyView.
Engineering the structural phase of materials is of paramount importance for both fundamental research and practical applications. In this Review, we summarize the recent progress in controlling the phases of atomically precise nanoclusters (APNCs) of gold, silver and copper, as well as bimetallic systems. The phase‐enabled material properties of APNCs
Yitong Wang, Avirup Sardar, Weijie Ji, Zhongyu Liu, Rongchao Jin   +4 more
wiley   +1 more source

Synergistic effect of Zinc Phthalocyanine (ZnPC)@MIL-101 framework and laser radiation on mcf-7 breast cancer cells: an experimental combination study [PDF]

Nanomedicine Journal
Objective(s): Zinc phthalocyanine (ZnPC), a potent photosensitizer for photodynamic therapy (PDT), often suffers from poor solubility and aggregation, limiting its efficacy.
Mahin Velayati, Zahra Sabouri, Ramin Rezaee, Mohammad Hasan Soheilifar, Hoda Keshmiri Neghab, Hashemi Ghoochani Samaneh, Alireza Hashemzadeh, Majid Darroudi   +7 more
doaj   +1 more source

Multifunctional Photosensitizer-Based Contrast Agents for Photoacoustic Imaging [PDF]

Scientific Reports, 2014
Photoacoustic imaging is a novel hybrid imaging modality combining the high spatial resolution of optical imaging with the high penetration depth of ultrasound imaging. Here, for the first time, we evaluate the efficacy of various photosensitizers that are widely used as photodynamic therapeutic (PDT) agents as photoacoustic contrast agents ...
Ho, Chris Jun Hui, Balasundaram, Ghayathri, Driessen, Wouter, McLaren, Ross, Wong, Chi Lok, Dinish, U. S., Attia, Amalina Binte Ebrahim, Ntziachristos, Vasilis, Olivo, Malini   +8 more
openaire   +2 more sources

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Bismuth-gold nanohybrid based nano photosensitizer to combat antimicrobial resistance

Scientific Reports
Antimicrobial resistance (AMR) leads to a decrease in the adequacy of antimicrobial agents and an increase in the rate of adverse effects and mortality. The main objective of this project is to investigate the synergistic effect of BiAu@NCLin-T1 and its ...
Atiyeh Nomani, Hamed Nosrati, Naser Faraji, Jalil Charmi, Siamak Javani   +4 more
doaj   +1 more source

Decoupling Activation and Preservation: Architectural Design Principles of Organic Frameworks for Selective Photocatalytic Methane Oxidation

Advanced Materials, EarlyView.
Selective methane (CH4) photooxidation emerges from architectural decoupling of activation and preservation. Programmable organic semiconductor frameworks spatially organize oxidative flux and intermediate residence, separating reaction zones from product domains to synchronize activation strength with stabilization and establish a selective oxidation ...
Minxian Zhang, Jie He, Jinqiang Zhang, Hongqi Sun, Shaobin Wang, Xiaoguang Duan   +5 more
wiley   +1 more source