Results 131 to 140 of about 13,390 (349)

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Improved Pilot-Plant-Scale Synthesis of Chlorin e6 and Its Efficacy as a Photosensitizer for Photodynamic Therapy and Photoacoustic Contrast Agent [PDF]

, 2022
Til Bahadur Thapa Magar, Rajeev Shrestha, Pallavi Gurung, Junmo Lim, Yong-Wan Kim   +4 more
openalex   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

A Bioorthogonal Antidote Against the Photosensitivity after Photodynamic Therapy

Advanced Science
As an effective and non‐invasive treatment modality for cancer, photodynamic therapy (PDT) has attracted considerable interest. With the recent advances in the photosensitizing agents, the fiber‐optic systems, and other aspects, its application is ...
Evelyn Y. Xue, Caixia Yang, Yimin Zhou, Dennis K. P. Ng   +3 more
doaj   +1 more source

Photoreactions between flavin coenzymes and skin-photosensitizing agents [PDF]

, 1963
L. Musajo
openalex   +1 more source

Dye-sensitized Solar Cell With Water Hyacinth (Eichhornia Crassipes) As Photosensitizer and Xanthan Gum As Thickening Agent in The Electrolyte [PDF]

, 2023
Tamrin Tamrin, Fikri Aditya Wisnu Pratama, H Hower, Hersyamsi Hersyamsi, E Saleh, GP Ariyani, I S Ramadhani   +6 more
openalex   +1 more source

Truncated Conjugate Structure Improves Solar‐Driven Hydrogen Peroxide Production Catalyzed by Benzobisthiazole‐Based Conjugated Polymers

Advanced Science, EarlyView.
In this work, a novel molecular design strategy was employed to truncate large‐scale conjugated structures in covalent polymer materials. This approach significantly enhances the catalyst’s light‐harvesting capability, prolongs the lifetime of photogenerated charge carriers, and improves catalytic activity, thereby offering a new conceptual pathway for
Cui Li, Qirui Wang, Shu Lin, Xianglin Xiang, Kezhen Qi   +4 more
wiley   +1 more source

Exploration of metallized phthalocyanines as potential alternative photosensitizers in photodynamic therapy

Archives of Advances in Biosciences
introduction: Photodynamic therapy (PDT) uses photosensitizers to generate reactive oxygen species (ROS) for selective cancer cell and pathogen destruction.
Franklin Vargas, Miguel Leon, Johany L Velásquez, Emily Acevedo, Valery John, Rubén Machado, Alvaro Alvarez-Aular   +6 more
doaj   +1 more source

Nuclear PARP1‐Targeted Photosensitizer as a Dual‐Mode DNA‐Damaging Agent and Immune Activator for Tumor Ablation (Adv. Healthcare Mater. 31/2023) [PDF]

, 2023
Peixia Li, Yayin Du, Jingru Qiu, Donghai Li, Guiling Li, Gang Shan   +5 more
openalex   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source