Results 291 to 300 of about 13,390 (349)
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Biodistribution of photosensitizing agents
International Journal of Biochemistry, 19931. The features of neoplasia which predict for drug responsiveness are rapid growth and/or inefficient repair of damage, especially to DNA. 2. PDT has the advantage of yielding responses regardless of the growth fraction of a tumor, and repair appears to play only a minor role. 3. While an entirely different spectrum of tumors can be targeted with PDT,
D, Kessel, K, Woodburn
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Photosensitivity Associated with Antibacterial Agents
Drug Safety, 1993Skin reactions following the interaction of photoactive drugs and ultraviolet or visible radiation are usually rapidly reversible after drug cessation. Within the antibacterial group, photosensitivity to sulphonamides, nalidixic acid, fluoroquinolones and tetracycline members have all been reported.
N J, Wainwright, P, Collins, J, Ferguson
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Photosensitization by selected anticancer agents
Biophysical Chemistry, 1990Novel anticancer anthrapyrazoles and anthracenediones are available as alternatives to the cardiotoxic clinical agents, doxorubicin and daunorubicin. Certain representatives of these new classes of compounds possess photosensitizing properties.
K, Reszka, J A, Hartley, J W, Lown
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Photosensitizing Therapeutic Agents
JAMA, 1960The antibacterial sulfonamides, the related group of hypoglycemic agents, the group of chlorothiazide diuretics, and the phenothiazine group of central sympathetic suppressants may induce cutaneous reactions when the patient is exposed to sunlight. There are numerous reports that demethylated chlortetracycline may act as a photosensitizing agent, and a
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Journal of the American Medical Association, 1939
My purpose in this paper is to report two cases of pigmentation—one resulting from a photosensitizing dye and the other from a toilet water—and to discuss briefly the parenteral and ingested photosensitizing substances as well as the topical photosensitizers.
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My purpose in this paper is to report two cases of pigmentation—one resulting from a photosensitizing dye and the other from a toilet water—and to discuss briefly the parenteral and ingested photosensitizing substances as well as the topical photosensitizers.
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Photodynamic Therapy with a New Photosensitizing Agent
Photomedicine and Laser Surgery, 2007Objective: The aim of this study was to investigate the cytotoxicity of octal-bromide zinc phthalocyanine (ZnPcBr 8 ) before and after irradiation with a low-power laser (AsGaAl) and analyze the effects of photodynamic therapy (PDT) on the nucleus of L929 cells.
Aline Helena Araujo, Machado +5 more
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Cutaneous photosensitivity diseases induced by exogenous agents
Journal of the American Academy of Dermatology, 1995Cutaneous photosensitivity diseases may be idiopathic, produced by endogenous photosensitizers, or associated with exogenous photosensitizers. Those caused by exogenous agents include phototoxicity, photoallergy, and the exacerbation or induction of systemic disorders in which photosensitivity is a prominent clinical manifestation. Phototoxic disorders
J W, Gould, M G, Mercurio, C A, Elmets
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IS PENICILLIN A PHOTOSENSITIZING AGENT?
Archives of Dermatology, 1946To the Editor :—Under the title "Is Penicillin a Photosensitizing Agent?" Dr. Orlando Canizares (Arch. Dermat. & Syph. 52 :17 [July] 1945) reports on an interesting case. Since penicillin is such an important drug, the question whether it is also a photosensitizer deserves careful attention; therefore, I should like to comment briefly on Dr. Canizares'
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Photosensitizers Binding to Nucleic Acids as Anticancer Agents
Future Medicinal Chemistry, 2016Cationic porphyrins (Prs) and phthalocyanines (Pcs) are strong photosensitizers that have drawn much attention for their potential in photodynamic therapy. These compounds have the interesting property of binding to nucleic acids, in particular G-rich quadruplex-forming sequences in DNA and RNA.
XODO, Luigi +2 more
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A carbohydrate-linked hypericinic photosensitizing agent
Monatshefte für Chemie - Chemical Monthly, 2008With respect to an enhanced solubility under physiological conditions, a carbohydrate-containing hypericin-based second-generation photosensitizer was prepared. Its photochemical properties were tested by means of the light-sensitized destruction of bilirubin IXα to be even better than those of the parent compound hypericin.
Joachim Zuschrader +2 more
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