Results 91 to 100 of about 954 (199)

Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates

Aggregate, Volume 7, Issue 3, March 2026.
This review highlights the construction of AIE active bioconjugates via click chemical or bioorthogonal reactions, and their applications in biosensing, bioimaging, and image‐guided treatment. The challenges and perspectives in the area are also discussed.
Xinzhe Yang, Miaomiao Kang, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Light‐Activated Multifunctional Nanoplatforms: Reshaping Combination Therapy to Overcome Multidrug Resistance in Breast Cancer

Small Structures, Volume 7, Issue 3, March 2026.
Multidrug resistance in breast cancer constitutes a major therapeutic obstacle. This review examines light‐activated nanoplatforms combining photothermal and photodynamic therapies to overcome this challenge. Through rational design, these systems enable spatiotemporal control, enhanced tumor targeting, and synergistic antitumor efficacy.
Xianghui Duan, Gangcui Li, Hong Wang, Yanan Zhou, Hai Du, Qin Sun, Fulan Zhao, Luyin Yang, Pan Liang, Wei Ren   +9 more
wiley   +1 more source

Exploring and leveraging aggregation effects on reactive oxygen species generation in photodynamic therapy

Aggregate
Aggregate‐level photodynamic therapy (PDT) has attracted significant interest and driven substantial advances in multifunction phototheranostic platforms. As exemplified by two typical instances of aggregation‐caused quenching of reactive oxygen species (
Zeyan Zhuang, Jianqing Li, Pingchuan Shen, Zujin Zhao, Ben Zhong Tang   +4 more
doaj   +1 more source

Advanced Hybrid Nano-Particles Peptides for Targeted Treatment of Pulmonary Fibrosis [PDF]

, 2023
The development of advanced hybrid nano-particles peptides for targeted treatment of pulmonary fibrosis represents a significant advancement in the field of respiratory medicine.
Yallam Sailaja, Saritha Pendlikatla, Prasanthi Samathoti, Amit Kumar Nigam, Mahendra Singh Ashawat, Manoj Kumar Katual, Zankhana Pramodchandra Sheth, Pydiraju Kondrapu
core   +1 more source

Synthesis and Photophysical Characterization of Axially Functionalized Silicon(IV) Naphthalocyanines with Phototheranostic Potential

ChemistryEurope, Volume 4, Issue 2, February 2026.
In this study, the synthesis and detailed photophysical characterization of SiNcs functionalized with structurally diverse axial ligands designed to enhance solubility and evaluate photophysical properties are reported. The lead compound, SiNc 3‐PP, demonstrates photothermal conversion efficiency of 62.1% and pronounced photoacoustic contrast at 810 nm,
Pedro M. R. Santos, Benjamin Proto, Debalina Mondal, Alicia Voge, Christine Hoskin, Hanyi Weng, Inês R. M. Santos, Kevin Stamplecoskie, João P. C. Tomé, Juan Chen, Nahyun Kwon, Gang Zheng   +11 more
wiley   +1 more source

Gold Rod-Polyethylene Glycol-Carbon Dot Nanohybrids as Phototheranostic Probes

Nanomaterials, 2018
Emphasis using phototheranostics has been placed on the construction of multifunctional nanoplatforms for simultaneous tumor diagnosis and therapy. Herein, we put forth a novel nanosized luminescent material using the incorporation of red emissive carbon
Yuefang Niu, Guo Ling, Li Wang, Shanyue Guan, Zheng Xie, Eran A. Barnoy, Shuyun Zhou, Dror Fixler   +7 more
doaj   +1 more source

Фосфолипидная система с адресным пептидом ангиопеп-2 для доставки хлорина е6 в исследовании in vitro [PDF]

The previously obtained phospholipid nanosystem for the delivery of the photosensitizer chlorine e6 was modified with a targeting ligand, the oligopeptide angiopep-2, exhibiting a high ability to transcytose through the blood-brain barrier.
Kostryukova, L.V., Pyatigorsky, A.M., Tereshkina, Y.A., Tikhonova, E.G.   +3 more
core   +2 more sources

GSH‐Depleted Platinum(II) Metallacycles to Turn On the NIR Emission in Boosting Synergistic Cancer Therapy

Aggregate, Volume 7, Issue 1, January 2026.
This is the first case of glutathione‐depleted and responsive platinum(II) metallacycles to turn on the NIR emission simultaneously. The combination of GSH depletion and ROS generation induces oxidative stress and immunogenic cell death (ICD) in tumor cells.
Qifei Shen, Kai Gao, Peijuan Zhang, Xuwei Luo, Jianye Yang, Pei Zhou, Yanzi Xu, Changhuo Xu, Lingjie Meng, Heng Wang, Chao Chen, Mingming Zhang, Dongfeng Dang   +12 more
wiley   +1 more source

Alleviating NIR-II emission quenching in ring-fused fluorophore via manipulating dimer populations for superior fluorescence imaging. [PDF]

Emission quenching resulting from fluorophore aggregation has long been a significant challenge in optimizing emission-based technologies, such as fluorescence imaging and optoelectronic devices.

core   +1 more source

Stimulator of interferon genes (STING)‐activating nanomedicines: Translating innate immune modulation into effective therapy for triple‐negative breast cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Graphical representation of STING‐activated nanomedicines is for effective treatment of triple‐negative breast cancer. Abstract Triple‐negative breast cancer (TNBC), marked by profound immunosuppressive complexity, poses a critical challenge in therapy due to the absence of hormone receptors in its phenotype, making it unavailable for conventional ...
Harshita Singhai, Taha Alqahtani, Humood Al Shmrany, Garima Gupta, Umesh Kumar Patil, Amirhossein Sahebkar, Prashant Kesharwani   +6 more
wiley   +1 more source