Results 71 to 80 of about 954 (199)

Intermolecular hydrogen‐bonded associates of BODIPYs drive controllable aggregates and enhanced NIR phototherapeutic performance

Smart Molecules, EarlyView.
This study herein presents the rational design and synthesis of a series of meso‐CF3‐substituted BODIPY dyes to achieve controllable molecular aggregation and enhanced near‐infrared (NIR) phototherapeutic performance. Abstract This study herein presents the rational design and synthesis of a series of meso‐CF3‐substituted BODIPY dyes to achieve ...
Siying Gou, Zhe Xun, Peijun Yang, Xin Li, Dongxiang Zhang, Jianjun Du, Shuo Li, Xin‐Dong Jiang, Gaowu Qin   +8 more
wiley   +1 more source

The Fast‐Growing Field of Cancer Immunotherapy Based on Aggregation‐Induced Emission

Aggregate
Cancer immunotherapy is a groundbreaking treatment that utilizes the body's immune system to fight against cancers. Despite the clinical application of several immunotherapeutic agents, challenges persist, including limited patient responsiveness and ...
Zhijie Lin, Tingting He, Miaomiao Kang, Wei Xie, Dong Wang, Ben Zhong Tang   +5 more
doaj   +1 more source

Nanoparticles-based phototherapy systems for cancer treatment : Current status and clinical potential [PDF]

, 2022
Remarkable progress in phototherapy has been made in recent decades, due to its non-invasiveness and instant therapeutic efficacy. In addition, with the rapid development of nanoscience and nanotechnology, phototherapy systems based on nanoparticles or ...
Fontana, Flavia, Han, Huijie, Li, Jiachen, Santos, Helder A., Shahbazi, Mohammad -Ali, Tapeinos, Christos, Wang, Shiqi   +6 more
core   +2 more sources

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Dual‐Activatable Nano‐Immunomodulator for NIR‐II Fluorescence Imaging‐Guided Precision Cancer Photodynamic Immunotherapy

Advanced Science
Photodynamic immunotherapy which combines photodynamic therapy with immunotherapy has become an important and effective method for the treatment of cancer.
Shanchao Diao, Zhifan Zhang, Sijun Zhao, Qiang Li, Xiaolong Zhang, Xiangqi Yang, Zhiwei Xu, Mingming Liu, Wen Zhou, Rutian Li, Chen Xie, Quli Fan   +11 more
doaj   +1 more source

Environmentally sensitive photosensitizers enable targeted photodynamic ablation of Gram-positive antibiotic resistant bacteria [PDF]

, 2023
Bacterial infections remain among the biggest challenges to human health, leading to high antibiotic usage, morbidity, hospitalizations, and accounting for approximately 8 million deaths worldwide every year.
Benson, Sam, Dhaliwal, Kevin, Kiang, Alex, Lal, Navata, Lochenie, Charles, Mills, Beth, Padinjarottu Charinjathil Mohanan, Syam Mohan, Vendrell, Marc, Williams, Gareth   +8 more
core   +2 more sources

Extended π‐Conjugated Bridge Strategy for an Enhanced Stokes Shift and Multimodal Imaging‐Guided Type I/II Photodynamic Therapy Integrated With Photothermal Therapy

Aggregate, Volume 7, Issue 5, May 2026.
A “unity of a thousand blades” phototheranostic nanoplatform (TDTIC‐M) has been designed to achieve comprehensive theranostic capabilities for breast cancer, including specific subcellular targeting, near‐infrared I/II fluorescence imaging, photoacoustic imaging, photothermal imaging, and multimodal image‐guided synergistic Type I/II photodynamic ...
Chanyuan Jin, Feifan Zhao, Yane Zhang, Jiujiang Ji, Yuanyuan Han, Xiaoli Lu, Ping Wu, Chen Chen, Yan Yang, Yongqiang Feng, Jianfeng Huang, Haijun Ma, Mei Tian, Yen Wei   +13 more
wiley   +1 more source

Complexity made easy: Aggregation‐induced emission small molecules for cancer diagnosis and phototherapies

Aggregate
Phototheranostics has garnered sustained attention due to its significant potential for revolutionizing conventional cancer treatment strategies. While being one of the most commonly employed strategies for constructing phototheranostic systems by ...
Luojia Chen, Si‐Ling Chen, Yuncong Yuan, Xiang Leng, Xiaoyu Xu, Jingyuan Chen, Jiayi Shi, Kun Qian, Yuanlong Xie, Qihang Ding, Zhen Cheng, Meijia Gu   +11 more
doaj   +1 more source

Squaraine nanoparticles for optoacoustic imaging-guided synergistic cancer phototherapy

Nanophotonics, 2023
The unique optical properties of squaraine dyes make them promising for cancer phototheranostics, but the reported squaraines for in vivo treatments mainly rely on their photothermal effect, where monotherapy cannot achieve the desired therapeutic effect.
Chen Xiao, Ma Xiaopeng, Yang Gui, Huang Guan, Dai Haibing, Liu Nian, Yu Jianbo   +6 more
doaj   +1 more source

Nanographene-Based Polymeric Nanoparticles as Near-Infrared Emissive Neuronal Tracers [PDF]

Precise tracking of axonal transport is key to deciphering neuronal functions. To achieve long-term imaging at both ultrastructural and macroscopic resolutions, it is critical to develop fluorescent transport tracers with high photostability and ...
Emily, Maria Fransiska, Guillaud, Laurent, Hanayama, Hiroki, Kabe, Ryota, Moshniaha, Liliia, Narita, Akimitsu, Terenzio, Marco, Xu, Xiushang, Zhao, Hao   +8 more
core   +2 more sources