Results 131 to 140 of about 47,999 (247)

Unilateral Hyperkeratotic Lesions With a Sporotrichoid Pattern

open access: yes
JEADV Clinical Practice, EarlyView.
José González Fernández   +4 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear   +6 more
wiley   +1 more source

Efficacy of Local and Whole-Body Phototherapy for the Treatment of Various Types of Alopecia Areata. [PDF]

open access: yesPhotodermatol Photoimmunol Photomed
Yamamoto A   +6 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell   +6 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

open access: yesRare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan   +5 more
wiley   +1 more source

Constraints and Frugal Innovation: Enabling Sustainable Production Through the New Product Development Process

open access: yesSustainable Development, EarlyView.
ABSTRACT This paper advances understanding of how constraint‐based thinking fosters sustainable innovation under resource limitations. Based on five case studies of small and medium‐sized enterprises and research groups developing frugal medical devices across diverse regions, it identifies how market, infrastructure, and user constraints shape design ...
Zulfiya Ukbaeva   +2 more
wiley   +1 more source

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