Phase 1 study of balinatunfib, an oral inhibitor of TNFR1 signal in mild‐to‐moderate psoriasis
Balinatunfib is the first oral, small molecule selective inhibitor of TNFR1 signaling. The results of this study indicate that balinatunfib treatment was tolerable with no serious or severe adverse events in patients with mild‐to‐moderate psoriasis and showed clinical responses.
Nassr Nassr +10 more
wiley +1 more source
Hyperbilirubinemia monitoring program in infants ≥ 35 weeks: a Brazilian quality improvement study. [PDF]
Grillo ALY, Marba STM, Caldas JPS.
europepmc +1 more source
French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault +51 more
wiley +1 more source
The SKINERGY study will investigate six immune‐mediated inflammatory skin diseases through a nationwide collaboration across all Dutch university medical centres. Involving 720 patients and 120 healthy volunteers, it is aimed at generating a high‐quality dataset to identify biomarkers that enable personalized treatment strategies and improved disease ...
N. G. Koster +68 more
wiley +1 more source
Microneedles meet photomedicine: emerging strategies for diagnosis and therapy of skin diseases. [PDF]
Zhou Z +6 more
europepmc +1 more source
Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley +1 more source
Bimekizumab efficacy and safety in Chinese patients with psoriasis in the BE SHINING Phase 3 study
In Chinese patients with moderate to severe plaque psoriasis, bimekizumab treatment was well tolerated and led to significantly higher clinical response rates versus placebo, including complete skin clearance. These findings were consistent with global studies and suggest that bimekizumab is an effective treatment option for Chinese people living with ...
Lin Cai +11 more
wiley +1 more source
The Effectiveness of Home-Based Phototherapy in Vitiligo: A Systematic Review and Meta-Analysis. [PDF]
Xireaili F +6 more
europepmc +1 more source
Medical Phototherapy Malpractice and Legal Precedents in North America (1983–2025)
International Journal of Dermatology, EarlyView.
Ghassan Barnawi +6 more
wiley +1 more source
Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source

