Results 211 to 220 of about 32,454 (332)

Selectivity and anti‐tumor immune elevation by vascular‐targeted photodynamic therapy of mouse orthotopic bladder cancer model

open access: yesPhotochemistry and Photobiology, EarlyView.
Vascular‐targeted photodynamic therapy (VTP) using the photosensitizer WST11 is a non‐surgical tumor ablation approach. Light activation of WST11 leads to excessive generation of reactive oxygen species, which causes tumor vascular arrest, followed by destruction of tumor blood vessels and tumor necrosis.
Jie Chen   +8 more
wiley   +1 more source

Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole

open access: gold, 2002
A. Miroššay   +5 more
openalex   +1 more source

Cutaneous photosensitivity of phototheranostic porphyrin–lipid nanoparticles

open access: yesPhotochemistry and Photobiology, EarlyView.
Porphyrin‐lipid nanoparticles (PORPHYSOMES) exhibit significantly less severe and shorter‐lasting skin photosensitivity to sunlight compared to a therapeutically equivalent dose of porfimer sodium (PHOTOFRIN) in a rat skin model. The difference was due to altered intradermal distribution and faster clearance of PORPHYSOMES from skin after intravenous ...
Michael S. Valic   +20 more
wiley   +1 more source

Taurine deficiency is a cause of vigabatrin‐induced retinal phototoxicity [PDF]

open access: green, 2009
Firas Jammoul   +13 more
openalex   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

open access: yesPhotochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina   +3 more
wiley   +1 more source

Integrin targeted photodynamic therapy in patient‐derived glioblastoma spheroids

open access: yesPhotochemistry and Photobiology, EarlyView.
A novel targeted photodynamic therapy (PDT) agent, SiPc‐2c(RGDfK), was used to treat patient‐derived glioma stem cell spheroids expressing varying levels of the V3 integrin. The quantitative measurement of cytotoxicity following treatment demonstrated the therapeutic efficacy of SiPc‐2c(RGDfK) on V3‐expressing single spheroids, effectively ...
Miriam Roberto   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy