Results 211 to 220 of about 32,162 (236)
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Ocular fluorescein phototoxicity
Applied Optics, 1987Fluorescein angiography is one of the most commonly used diagnostic techniques in modern ophthalmology. Prior to this study, recommendations on the phototoxicity of this technique were based on light levels alone (i.e., without fluorescein present). Using a rabbit model to demonstrate retinal damage, intravenous sodium fluorescein was found to reduce ...
Bernard F. Hochheimer +2 more
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British Journal of Dermatology, 2004
Both cigarette smoke and ultraviolet (UV) radiation are known to cause changes of the skin which can be regarded as premature ageing.To assess the theory that the effects of these two exposures could be linked by a phototoxic action of cigarette smoke.A photohaemolysis test was used, in which human erythrocytes were incubated with cigarette smoke ...
Bernhard Przybilla +4 more
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Both cigarette smoke and ultraviolet (UV) radiation are known to cause changes of the skin which can be regarded as premature ageing.To assess the theory that the effects of these two exposures could be linked by a phototoxic action of cigarette smoke.A photohaemolysis test was used, in which human erythrocytes were incubated with cigarette smoke ...
Bernhard Przybilla +4 more
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Phototoxic Furanoquinolines of the Rutaceae
Planta Medica, 1981Dictamnine, isodictamnine, 7-demethylskimmianine, maculosidine and maculine were shown to be phototoxic to certain bacteria and yeasts in long wave UV light. Dose response curves with dictamnine and 8-methoxypsoralen in UV light were compared using E. COLI and SACCHAROMYCES CEREVISIAE.
E. A. Graham +3 more
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Phototoxic and Photoallergic Reactions
1992Phototoxic and photoallergic reactions may be induced by the topical application of a compound followed by irradiation — phototoxic and photoallergic contact reactions. Alternatively, reactions may be induced after the systemic absorption of a compound followed by irradiation.
Roy A. Palmer, Ian R. White
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Mechanisms of quinolone phototoxicity
Toxicology Letters, 1998We examined the mechanisms of quinolone phototoxicity in vivo and in vitro. Simultaneous p.o. administration of a quinolone and ultraviolet-A (UVA) irradiation for 4 h induced auricular skin inflammation in BALB/c mice, including edema and neutrophil infiltration in the dermis.
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Phototoxicity of Shalimar Perfume
Archives of Dermatology, 1966Application of Shalimar perfume to the skin denuded of stratum corneum, followed by irradiation by the proper ultraviolet energy, produced intense phototoxic reactions in ten out of ten normal patients tested.
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Photochemistry and phototoxicity studies of flutamide, a phototoxic anti-cancer drug
Journal of Photochemistry and Photobiology B: Biology, 2000The phototoxic anti-cancer drug flutamide is photolabile under UV-B light in either aerobic or anaerobic conditions. Irradiation of a methanol solution of this drug produces several photoproducts, one by photoreduction of the nitro group, one by rupture of the aromatic-NO2 bond of the parent compound, two as a result of the rupture of the CO-NH bond ...
Alberto Fuentes +5 more
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Ultraviolet Phototoxicity to the Retina
Eye & Contact Lens: Science & Clinical Practice, 2011This overview of ultraviolet (UV) phototoxicity considers the interaction of UVA and short-wavelength VIS light with the retina and retinal pigment epithelium.The damage mechanisms underlying UV retinal phototoxicity are illustrated with a literature survey and presentation of experimental results.Depending on the wavelength and exposure duration ...
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Phototoxic potential of quinolones
Journal of Photochemistry and Photobiology B: Biology, 1991The photohaemolytic potentials of the quinolones oxolinic acid, pipemidic acid, rosoxacin, norfloxacin, ciprofloxacin and M-193324 (synthesis intermediary) were evaluated and compared with the photohaemolysis induced by nalidixic acid. Quinolones with a piperazine group in position 7 (pipemidic acid, norfloxacin and ciprofloxacin) did not induce ...
Fernando Vargas +3 more
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Screening for Ocular Phototoxicity
International Journal of Toxicology, 2002Normally light transmission through the eye is benign and serves to direct vision and circadian rhythm. However, with very intense light exposure, or with ambient light exposure to the aged eye and/or young or adult eye in the presence of light-activated (photosensitizing) drugs or dietary supplements, cosmetics, or diagnostic dyes, light can be ...
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