Results 261 to 270 of about 34,272 (324)

Implanted Miniature Light Devices for Phototherapeutics

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
Modern phototherapeutics has many attractive features; however, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts usage to superficial sites of disease. To mitigate this major problem, researchers and clinicians are actively developing miniature implanted light devices that can be implanted within a
Hailey S. Sanders   +5 more
wiley   +1 more source

BRIGHT Enables High‐SNR Live‐Cell Imaging of Non‐Repetitive Sequences via Bivalent Fluorescent Nanobody‐Mediated Cascade‐Dependent Illumination

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng   +9 more
wiley   +1 more source

Flash Photodynamic Therapy – How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut   +3 more
wiley   +1 more source

Optimizing Sunscreen Safety: The Impact of TiO<sub>2</sub> Particle Size on Toxicity and Biocompatibility. [PDF]

open access: yesNanomaterials (Basel)
Maddaleno AS   +5 more
europepmc   +1 more source

Disordered Glass Nanowire Substrates Produce in Vivo‐Like Astrocyte Morphology Revealed by Low‐Coherence Holotomography

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
Low‐coherence holotomography reveals that disordered nanowire substrates guide astrocyte morphology toward branched, in vivo–like star‐shaped morphology, emphasizing the role of biophysical cues in shaping neural cell behavior. The developed nanostructured platform offers a new route to study astrocytes for neurobiology studies. Abstract Astrocytes are
Pooja Anantha   +11 more
wiley   +1 more source

A Dual‐Locking G‐Quadruplex DNA Targeting Strategy Based on a Tumor‐Accumulating Porphyrin‐Ruthenium(II) Conjugate for Type I Photodynamic Therapy

open access: yesAggregate, Volume 7, Issue 1, January 2026.
This study identifies PorRu as a “dual‐lock” G‐quadruplex binder, which also serves as a tumor‐targeting Type I photosensitizer. This agent overcomes the limitations of oxygen‐dependent PDT, providing a novel strategy for precise HCC therapy. ABSTRACT The hypoxic tumor microenvironment severely limits the effectiveness of photodynamic therapy (PDT) in ...
Qiong Wu   +6 more
wiley   +1 more source

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