Results 291 to 300 of about 34,272 (324)
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Ophthalmology Clinics of North America, 2001
Although the occurrence of iatrogenic light-induced retinal toxicity is beyond doubt, several issues remain to be studied further. These include conflicting reports regarding the wavelength of light that is most hazardous; what mechanism contributes more significantly in the pathogenesis of light-induced retinal toxicity-photochemical or photothermal ...
L, Verma, P, Venkatesh, H K, Tewari
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Although the occurrence of iatrogenic light-induced retinal toxicity is beyond doubt, several issues remain to be studied further. These include conflicting reports regarding the wavelength of light that is most hazardous; what mechanism contributes more significantly in the pathogenesis of light-induced retinal toxicity-photochemical or photothermal ...
L, Verma, P, Venkatesh, H K, Tewari
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Journal of Photochemistry and Photobiology B: Biology, 1988
The human eye is constantly exposed to sunlight and artificial lighting. Therefore the eye is exposed to UV-B (295-320 nm), UV-A (320-400 nm), and visible light (400-700 nm). Light is transmitted through the eye and then signals the brain directing both sight and circadian rhythm. Therefore light absorbed by the eye must be benign.
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The human eye is constantly exposed to sunlight and artificial lighting. Therefore the eye is exposed to UV-B (295-320 nm), UV-A (320-400 nm), and visible light (400-700 nm). Light is transmitted through the eye and then signals the brain directing both sight and circadian rhythm. Therefore light absorbed by the eye must be benign.
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Ocular fluorescein phototoxicity
Applied Optics, 1987Fluorescein angiography is one of the most commonly used diagnostic techniques in modern ophthalmology. Prior to this study, recommendations on the phototoxicity of this technique were based on light levels alone (i.e., without fluorescein present). Using a rabbit model to demonstrate retinal damage, intravenous sodium fluorescein was found to reduce ...
B F, Hochheimer, G A, Lutty, S A, D'Anna
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Phototoxicity of chlorpromazine
Journal of Medicinal Chemistry, 1979The constitution of chlorpromazine has been studied in the context of its phototoxicity. Electron transfer from the side chain to the aromatic nucleus of the drug contributes to its instability to light. Even without the side chain, however, chlorophenothiazines appear to be very photolabile, so that it is unlikely that nonphototoxic analogues of ...
N J, Bunce, Y, Kumar, L, Ravanal
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JAMA, 1979
Ignorance of phototoxicity by the general biomedical community constitutes a health hazard. Certain food colorants and dyes proposed for use in angiography produce lethal effects in cells and whole organisms on light exposure but not in the dark. Yet light-relatedness is usually neglected in toxicity studies.
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Ignorance of phototoxicity by the general biomedical community constitutes a health hazard. Certain food colorants and dyes proposed for use in angiography produce lethal effects in cells and whole organisms on light exposure but not in the dark. Yet light-relatedness is usually neglected in toxicity studies.
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Archives of Pharmacal Research, 1999
Melatonin (MLT), N-acetyl-5-methoxytryptamine, is mainly secreted by the pineal gland. The ultraviolet (UV), infrared (IR) and 1H-NMR spectra of irradiated and non-irradiated MLT were measured, and phototoxicity tests of MLT, anthracene (positive control) and sodium lauryl sulfate (SLS, negative control) were performed.
Y O, Kim +6 more
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Melatonin (MLT), N-acetyl-5-methoxytryptamine, is mainly secreted by the pineal gland. The ultraviolet (UV), infrared (IR) and 1H-NMR spectra of irradiated and non-irradiated MLT were measured, and phototoxicity tests of MLT, anthracene (positive control) and sodium lauryl sulfate (SLS, negative control) were performed.
Y O, Kim +6 more
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Dermatology, 1996
The radiation from quartz halogen light bulbs has been reported to cause erythema in humans and skin tumors in experimental animals.The objective of this study was to determine the relative risk of injury to humans due to the radiation from these lamps.We studied a 12-volt 50-watt quartz halogen lamp. We measured its ultraviolet output spectrum and the
E, Bloom +4 more
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The radiation from quartz halogen light bulbs has been reported to cause erythema in humans and skin tumors in experimental animals.The objective of this study was to determine the relative risk of injury to humans due to the radiation from these lamps.We studied a 12-volt 50-watt quartz halogen lamp. We measured its ultraviolet output spectrum and the
E, Bloom +4 more
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Phototoxicity and photoallergy
Seminars in Cutaneous Medicine and Surgery, 1999Photosensitivity may be phototoxic or photoallergic. Phototoxicity is much more common. There are 2 types of phototoxicity: photodynamic, which requires oxygen, and nonphotodynamic, which does not. Reactions induced by porphyrin molecules, coal tar derivatives, and many drugs are photodynamic.
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Cutaneous phototoxicity reactions
British Journal of Dermatology, 1986This paper reviews some potential mechanisms of cutaneous phototoxicity and discusses selected methods of predicting and ranking phototoxic reactions. Phototoxicity is a non-immunological reaction that is induced by the action of light on a photoactive chemical. The phototoxic chemical may be either exogenous or endogenous, and if exogenous may include
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