Results 151 to 160 of about 123,318 (307)

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

In Vitro analysis of the effect of mono-(2-ethylhexyl) phthalate (MEHP) exposure on macrophage inflammatory responses in relationship to Leydig cell steroid production

Frontiers in Toxicology
Macrophages, essential components of the innate immune system, are considered to be involved in the regulation of Leydig cell steroidogenesis, though by mechanisms that remain uncertain.
Akhil Adla, Allison Lunney, Barry Zirkin, Kassim Traore   +3 more
doaj   +1 more source

Pregnancy lipidomic profiles and DNA methylation in newborns from the CHAMACOS cohort. [PDF]

, 2019
Lipids play a role in many biological functions and the newly emerging field of lipidomics aims to characterize the varying classes of lipid molecules present in biological specimens.
Bradman, Asa, Eskenazi, Brenda, HOLLAND, Nina, Huen, Karen, Lee, Douglas, Tindula, Gwen   +5 more
core  

Bisphenols and Phthalates in Bottled Mineral Water: First Evidence of Co‐Occurrence, Estrogenic Activity, and Health Risk in Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), its structural analogs, and phthalates are synthetic chemicals widely used, with documented endocrine‐disrupting activity. This study aimed to develop and validate a selective multiresidue analytical method for the simultaneous determination of BPA, 10 bisphenol analogs, and six phthalates in PET‐bottled mineral water.
Giulia Boito Reyes, Lucas Correia Gonçalves, Fernanda Cristina Iba Molinari, José Eduardo Gonçalves   +3 more
wiley   +1 more source

Urine Phthalate Metabolites are Elevated in Patients with Esophageal Squamous Cell Carcinoma and Associated with Advanced Cancer Stage and Poor Survival

Cancer Management and Research
Yen-Hao Chen,1– 4 Wan-Ting Huang,5 Wen-Chin Lee,6 Ching-Mei Chen,5 Fu-Jen Cheng,7 Chia-Te Kung,7 Chin-Chou Wang,8 Liang-Jen Wang,9 Yu-Che Ou,10 Shau-Hsuan Li1 1Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung ...
Chen YH, Huang WT, Lee WC, Chen CM, Cheng FJ, Kung CT, Wang CC, Wang LJ, Ou YC, Li SH   +9 more
doaj  

Endocrine-Disrupting Chemicals Exposure and Neurocognitive Function in the General Population: A Community-Based Study

Toxics
Background: Endocrine-disrupting chemicals (EDCs) are pervasive in everyday environments. The impacts of these chemicals, along with EDC-related lifestyle and dietary habits on neurocognitive function, are not well understood.
Feng-Chieh Su, Yi-Chia Wei, Chiao-Yin Sun, Heng-Jung Hsu, Chin-Chan Lee, Yih-Ting Chen, Heng-Chih Pan, Cheng-Kai Hsu, Yun-An Liu, Chun-Yu Chen   +9 more
doaj   +1 more source

Trouble in Toyland: The 25th Annual Survey of Toy Safety [PDF]

, 2010
Outlines findings on toys that may pose choking hazards or contain lead, phthalates, or other toxins, developments in federal and international regulations, and recommendations for consumers, policy makers, and the Consumer Product Safety ...

core  

Gas check prevention during calendering of poly(vinyl chloride) films using poly(caprolactone)‐based additives

Journal of Vinyl and Additive Technology, Volume 31, Issue 2, Page 441-452, March 2025.
Three poly(caprolactone) (PCL)‐based additives of differing molecular weights were used as a secondary plasticizer to prevent gas checks in PVC films produced through calendering. Results showed that chemical and physicochemical properties influence the prevention or reduction of gas checks, unlike rheological properties including complex viscosity and
Luis F. Alvarez, Kushal Panchal, Richard L. Leask, Milan Maric, Jim A. Nicell   +4 more
wiley   +1 more source

Acute pulmonary pathology and sudden death in rats following the intravenous administration of the plasticizer, DI (2-ethylhexyl) phthalate, solubilized with Tween surfactants [PDF]

Intravenous administration of 200-300 mg/kg of di(2-ethylhexyl)phthalate (DEHP) solubilized in aqueous solutions of several Tween surfactants caused respiratory distress in rats.
Hutchins, G. M., Rubin, R. J., Schulz, C. O.   +2 more
core   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source