Characterizations of the multi-kingdom gut microbiota in Chinese patients with gouty arthritis
BMC Microbiology, 2023 Objective The gut microbial composition has been linked to metabolic and autoimmune diseases, including arthritis. However, there is a dearth of knowledge on the gut bacteriome, mycobiome, and virome in patients with gouty arthritis (GA).
Changming Chen +26 more
doaj +1 more source
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier +4 more
wiley +1 more source
Coccolithoviruses: A Review of Cross-Kingdom Genomic Thievery and Metabolic Thuggery
Viruses, 2017 Coccolithoviruses (Phycodnaviridae) infect and lyse the most ubiquitous and successful coccolithophorid in modern oceans, Emiliania huxleyi. So far, the genomes of 13 of these giant lytic viruses (i.e., Emiliania huxleyi viruses—EhVs) have been sequenced,
Jozef I. Nissimov +6 more
doaj +1 more source
The effects of stress on gut virome: Implications on infectious disease and systemic disorders
MicrobiologyOpen, Volume 13, Issue 5, October 2024.Stress conditions can weaken the host's immune system, affecting the entire gut–brain axis. Concurrently, disruptions in the composition of the gut microbiota are associated with exacerbations of diseases. This review explores the complex interplay between stress, gut virome, and the host immune system.
Francesca Talarico +5 more
wiley +1 more source
Isolation and characterization of a virus infecting the freshwater algae Chrysochromulina parva
, 2015 Water samples from Lake Ontario, Canada were tested for lytic activity against the freshwater haptophyte algae Chrysochromulina parva. A filterable lytic agent was isolated and identified as a virus via transmission electron microscopy and molecular ...
Short, S.M. +5 more
core +1 more source
First Insights into the Viral Communities of the Deep-sea Anoxic Brines of the Red Sea
Genomics, Proteomics & Bioinformatics, 2015 The deep-sea brines of the Red Sea include some of the most extreme and unique environments on Earth. They combine high salinities with increases in temperature, heavy metals, hydrostatic pressure, and anoxic conditions, creating unique settings for ...
André Antunes +7 more
doaj +1 more source
Temporal Variability of Virioplankton during a Gymnodinium catenatum Algal Bloom
Microorganisms, 2020 Viruses are key biogeochemical engines in the regulation of the dynamics of phytoplankton. However, there has been little research on viral communities in relation to algal blooms.
Xiao-Peng Du +5 more
doaj +1 more source
Genomic and biogeographic characterisation of the novel prasinovirus Mantoniella tinhauana virus 1
Environmental Microbiology Reports, Volume 16, Issue 5, October 2024.Phylogenetic tree, virion morphology and global metagenomic abundance of Mantoniella tinhauana virus 1, a newly isolated and characterised prasinovirus. Abstract Mamiellophyceae are a ubiquitous class of unicellular green algae in the global ocean.
Elvira Rey Redondo +2 more
wiley +1 more source
Dinucleotide biases in the genomes of prokaryotic and eukaryotic dsDNA viruses and their hosts
Molecular Ecology, Volume 33, Issue 6, March 2024.Abstract The genomes of cellular organisms display CpG and TpA dinucleotide composition biases. Such biases have been poorly investigated in dsDNA viruses. Here, we show that in dsDNA virus, bacterial, and eukaryotic genomes, the representation of TpA and CpG dinucleotides is strongly dependent on genomic G + C content.
Diego Forni +3 more
wiley +1 more source
Rapidity of Genomic Adaptations to Prasinovirus Infection in a Marine Microalga
Viruses, 2018 Prasinoviruses are large dsDNA viruses commonly found in aquatic systems worldwide, where they can infect and lyse unicellular prasinophyte algae such as Ostreococcus.
Sheree Yau +5 more
doaj +1 more source