Results 101 to 110 of about 22,712,044 (375)

Bayesian phylogenetic analysis of combined data.

open access: yesSystematic Biology, 2004
The recent development of Bayesian phylogenetic inference using Markov chain Monte Carlo (MCMC) techniques has facilitated the exploration of parameter-rich evolutionary models. At the same time, stochastic models have become more realistic (and complex)
J. Nylander   +3 more
semanticscholar   +1 more source

Neuropeptide Ecdysis‐Triggering Hormone and Its Receptor Mediate the Fecundity Improvement of ‘Candidatus Liberibacter Asiaticus’‐Infected Diaphorina citri Females and CLas Proliferation

open access: yesAdvanced Science, EarlyView.
In CLas‐infected D. citri, CLas lowers 20E levels initially, relieving the suppression of ETH release. The subsequent increase in ETH levels upregulates its receptor DcETHR and activates the JH signaling pathway. The signaling cascade of 20E‐ETH/ETHR‐JH along with miR‐210, targeting DcETHR, boost female fecundity in CLas+ D.
Xiaoge Nian   +8 more
wiley   +1 more source

kSNP3.0: SNP detection and phylogenetic analysis of genomes without genome alignment or reference genome

open access: yesBioinform., 2015
UNLABELLED We announce the release of kSNP3.0, a program for SNP identification and phylogenetic analysis without genome alignment or the requirement for reference genomes. kSNP3.0 is a significantly improved version of kSNP v2.
S. Gardner, T. Slezak, B. Hall
semanticscholar   +1 more source

Phylogenetic Analysis of the Genes Responsible for Albinism: Albinism Phylogenetic Analysis

open access: yes, 2018
{"references": ["Sun W , Shen Y , Shan S , Han L , Li Y , Zhou Z , Zhong Z , Chen J Identification of TYR mutations in patients with oculocutaneous albinism. Mol Med Rep. 2018 Jun;17(6):8409-8413. doi: 10.3892/mmr.2018.8881. Epub 2018 Apr 13.", "Markus N. Preising,1, 2 Hedwig Forster,1 Miriam Gonser,1 Birgit Lorenz1,2; Molecular Vision 2011; 17:939-948
Pandey, Shikha   +2 more
openaire   +2 more sources

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

open access: yesAdvanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal   +23 more
wiley   +1 more source

Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin**

open access: yesAngewandte Chemie International Edition, Volume 61, Issue 51, December 19, 2022., 2022
Corramycin is a novel natural product produced by the myxobacterium Corallococcus coralloides. The structure, extraordinary total synthesis and biosynthesis of the antibiotic is described for the first time. Its promise as an in vivo septicemia model, the absence of cross‐resistance with commonly used antibiotic classes, and the lack of cytotoxicity ...
Cédric Couturier   +32 more
wiley   +1 more source

Does Phylogenetic Proximity Explain Nestedness in Mutualistic Ecosystems? [PDF]

open access: yesarXiv, 2011
We investigate how the pattern of contacts between species in mutualistic ecosystems is affected by the phylogenetic proximity between the species of each guild. We develop a dynamical model geared to establish the role of such proximity in the emergence of a nested pattern of contacts.
arxiv  

A Bayesian Phylogenetic Hidden Markov Model for B Cell Receptor Sequence Analysis [PDF]

open access: yes, 2019
The human body is able to generate a diverse set of high affinity antibodies, the soluble form of B cell receptors (BCRs), that bind to and neutralize invading pathogens. The natural development of BCRs must be understood in order to design vaccines for highly mutable pathogens such as influenza and HIV.
arxiv   +1 more source

Poxvirus genomes: a phylogenetic analysis

open access: yesJournal of General Virology, 2004
The evolutionary relationships of 26 sequenced members of the poxvirus family have been investigated by comparing their genome organization and gene content and by using DNA and protein sequences for phylogenetic analyses. The central region of the genome of chordopoxviruses (ChPVs) is highly conserved in gene content and arrangement, except for some ...
Paul Kellam   +3 more
openaire   +3 more sources

Integrating Dense Genotyping with High‐Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang   +11 more
wiley   +1 more source

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