Results 211 to 220 of about 2,484,078 (389)

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

open access: yesAnnals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf   +8 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Author response for "Taxonomic, phylogenetic and functional diversity of understorey plants respond differently to environmental conditions in European forest edges"

open access: gold, 2021
Karen De Pauw   +25 more
openalex   +1 more source

Functional and Phylogenetic Diversity [PDF]

open access: yesJournal of Phylogenetics & Evolutionary Biology, 2016
openaire   +1 more source

Ruminant macroevolution: a phylogenetic approach based on extant faunas [PDF]

open access: yes, 2013
Cantalapiedra, Juan L.   +2 more
core   +1 more source

Unraveling Synthetase's Mode of Action: The Pyrrolysyl‐tRNA Synthetase Dimer Uses Secondary Binding Sites in the Cell

open access: yesAngewandte Chemie International Edition, EarlyView.
The pyrrolysyl‐tRNA synthetase dimer exhibits an alternating mode of action of its monomers within its catalytic cycle, which is realized upon occupation of secondary binding sites located at the intermonomer interfaces outside the catalytic binding site.
Jessica Dröden   +6 more
wiley   +1 more source

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