Results 91 to 100 of about 96,348 (290)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Cherry picking in forests: A new characterization for the unrooted hybrid number of two phylogenetic trees [PDF]

Discrete Mathematics & Theoretical Computer Science
Phylogenetic networks are a special type of graph which generalize phylogenetic trees and that are used to model non-treelike evolutionary processes such as recombination and hybridization. In this paper, we consider {\em unrooted} phylogenetic networks,
Katharina T. Huber, Simone Linz, Vincent Moulton   +2 more
doaj   +1 more source

Transformations to Simplify Phylogenetic Networks

Bulletin of Mathematical Biology
The evolutionary relationships between species are typically represented in the biological literature by rooted phylogenetic trees. However, a tree fails to capture ancestral reticulate processes, such as the formation of hybrid species or lateral gene transfer events between lineages, and so the history of life is more accurately described by a rooted
Johanna Heiss, Daniel H. Huson, Mike Steel   +2 more
openaire   +4 more sources

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Phylogenetic consensus networks: Computing a consensus of 1-nested phylogenetic networks

, 2021
An important and well-studied problem in phylogenetics is to compute a \emph{consensus tree} so as to summarize the common features within a collection of rooted phylogenetic trees, all whose leaf-sets are bijectively labeled by the same set~(X) of species.
Huber, Katharina T., Moulton, Vincent, Spillner, Andreas   +2 more
openaire   +2 more sources

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, EarlyView.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

THE NUMBER OF HOMOLOGS OF SOME ENZYMES IN THE TRYPTOPHAN BIOSYNTHESIS PATHWAY CORRELATES WITH THE PROPORTION OF PROTEINS ASSOCIATED WITH TRANSCRIPTION IN PLANTS

Вавиловский журнал генетики и селекции, 2015
The tryptophan biosynthesis pathway (TBP) is ubiquitous in most known organisms, being absent only from animals and some bacteria. It is conserved in plants, although various species differ in the number of TBP enzyme paralogs.
I. I. Turnaev, I. R. Akberdin, V. V. Suslov, D. A. Afonnikov   +3 more
doaj  

Asynchronous patterns in soil bacterial diversity and functional potentials along an alpine altitudinal gradient

Frontiers in Microbiology
IntroductionAltitudinal changes in soil bacterial diversity, composition, biotic interactions, and function are prevalent. However, the overall patterns and associations among these dimensions remain unclear, particularly in vulnerable alpine mountain ...
Xianping Li, Teng Li, Huixin Li
doaj   +1 more source

A Pan‐TE Map Reveals the Important Role of Transposable Elements in Gene Expression and Phenotypic Diversity in 2,311 Rapeseed Accessions

Advanced Science, EarlyView.
This study presents the first pan‐transposable element (TE) atlas in rapeseed, profiling over 8 million TEs across 2311 accessions. Integrative analyses reveal that TEs broadly shape gene expression through diverse regulatory mechanisms, with key insertions in BnaA03.FLC and BnaA09.CYP78A9 linked to flowering time and silique development.
Zhiquan Yang, Haiyan Fan, Yifan Chen, Jiawei Li, Minjian Chen, Yingying Tan, Liang Guo, Jintao Li, Kede Liu, Qing‐Yong Yang   +9 more
wiley   +1 more source