Results 191 to 200 of about 4,446,595 (349)

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T‐Cell Lymphoma

American Journal of Hematology, EarlyView.
ABSTRACT Nodal follicular helper T‐cell (TFH) lymphoma of the angioimmunoblastic (AITL) subtype has a dismal prognosis. Using whole‐exome sequencing (n = 124), transcriptomic (n = 78), and methylation (n = 40) analysis, we identified recurrent mutations in known epigenetic drivers (TET2, DNMT3A, IDH2R172) and novel ones (TET3, KMT2D).
Alyssa Bouska, Weiwei Zhang, Sunandini Sharma, Harald Holte, Rauf A. Shah, Waseem G. Lone, Mahfuza Afroz Soma, Ruimeng Yang, Xuxiang Liu, Syed Mehmood, Ravneet Singh Chawla, Luca Vincenzo Cappelli, Danilo Fiore, Qiang Gong, Tayla B. Heavican‐Foral, Jeffrey J. Cannatella, Catalina Amador, Aiza Arif, Lynette M. Smith, Soon Thye Lim, Choon Kiat Ong, Andrew L. Feldman, Ming‐Qing Du, Anamarija M. Perry, Laurence de Leval, Timothy C. Greiner, Kai Fu, Gunhild Trøen, Daniel Vodák, Sigve Nakken, Jan Delabie, David Weinstock, Stefano Pileri, Antonella Laginestra, KyeongJin Kim, Utpal Pajvani, Julie M. Vose, Dennis D. Weisenburger, Steven M. Horwitz, Sandeep Dave, Joseph Khoury, Giorgio Inghirami, Wing C. Chan, Javeed Iqbal   +43 more
wiley   +1 more source

Two complete chloroplast genomes of Ceratophyllum, an aquatic genus with unresolved phylogenetic position. [PDF]

Mitochondrial DNA B Resour
Ru S, Wu Z, Wang H, Li Q, Li T.
europepmc   +1 more source

SSU rRNA-based Phylogenetic Position of the Genera Amoeba and Chaos (Lobosea, Gymnamoebia): The Origin of Gymnamoebae Revisited [PDF]

, 2001
Ignacio Bolívar, José F. Fahrni, Alexey V. Smirnov, Jan Pawlowski   +3 more
openalex   +1 more source

Ruminant macroevolution: a phylogenetic approach based on extant faunas [PDF]

, 2013
Cantalapiedra, Juan L., Hernández Fernández, Manuel, Wörheide, Gert   +2 more
core   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone, Alessia Nisco, Luciana de Gennaro, Maria Tolomeo, Elisa Lorefice, Giuseppe Petrosillo, Silvia Russo, Donatella De Giovanni, Claudia Rita Catacchio, Francesca Romana Lepri, Mario Ventura, Simonetta Simonetti, Albina Tummolo, Maria Barile   +13 more
wiley   +1 more source

Comparative analysis of the organelle genomes of seven <i>Rosa</i> species (Rosaceae): insights into structural variation and phylogenetic position. [PDF]

Front Plant Sci
Zhang R, Liu S, Liu Y, Wei P, Xiang N, Zhao Y, Gao X, Yin Y, Qin L, Yuan T.   +9 more
europepmc   +1 more source

The mitochondrial genome of the pentastome parasite Raillietiella orientalis Hett, 1915 (Raillietiellida; Raillietiellidae) with notes on its phylogenetic position. [PDF]

Mitochondrial DNA B Resour, 2023
Palmisano JN, Farrell TM, Gustafson TM, Fitak RR.   +3 more
europepmc   +1 more source

Phylogenetic Position of Draco fimbriatus, with a Molecular Perspective on the Historical Biogeography of the Genus Draco (Reptilia: Agamidae).

, 2000
Masanao Honda, Hidetoshi Ota, Showichi Sengoku, Tsutomu Hikida   +3 more
openalex   +2 more sources

Taxon Sampling and the Phylogenetic Position of Passeriformes: Evidence from 916 Avian Cytochrome b Sequences [PDF]

, 2001
Kevin P. Johnson
openalex   +1 more source

Large-scale phylogenomic analysis reveals the phylogenetic position of the problematic taxon Protocruzia and unravels the deep phylogenetic affinities of the ciliate lineages.

Molecular Phylogenetics and Evolution, 2014
E. Gentekaki, M. Kolísko, M. Kolísko, V. Boscaro, Kelley J. Bright, F. Dini, G. Giuseppe, Yingchun Gong, C. Miceli, L. Modeo, R. Molestina, G. Petroni, S. Pucciarelli, A. Roger, S. Strom, D. Lynn   +15 more
semanticscholar   +1 more source