Results 51 to 60 of about 258,058 (308)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Increasing Taxa Sampling Provides New Insights on the Phylogenetic Relationship Between Eriobotrya and Rhaphiolepis

open access: yesFrontiers in Genetics, 2022
Eriobotrya (Rosaceae) is an economically important genus with around 30 species. It is widely distributed in tropical and warm temperate regions of Asia, with most of its species in China, Myanmar, and Vietnam.
Zhanghong Dong   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Neogastropod phylogenetic relationships based on entire mitochondrial genomes

open access: yesBMC Evolutionary Biology, 2009
Background The Neogastropoda is a highly diversified group of predatory marine snails (Gastropoda: Caenogastropoda). Traditionally, its monophyly has been widely accepted based on several morphological synapomorphies mostly related with the digestive ...
Zardoya Rafael   +2 more
doaj   +1 more source

Assessment of upper premolar morphological traits as reliable phylogenetic indicators [PDF]

open access: yes, 2002
Upper premolar size and cusp heteromorphy have been used in several studies that argue for alternative phyletic placements of early and middle Miocene fossil hominoids relative to extant primate clades.
Blundell, Louie Chantale
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Four New Sudanonautes Species of Freshwater Crabs (Crustacea: Decapoda: Potamonautidae) from Cameroon, Central Africa

open access: yesDiversity
Four new species of freshwater crab are described from material collected in northern and southwestern Cameroon and assigned to Sudanonautes Bott, 1955. Sudanonautes cameroonensis sp. n., S. eyimba sp. n., S. ngaoundere sp. n. and S. nkam sp.
Pierre A. Mvogo Ndongo   +3 more
doaj   +1 more source

Origin of Prunus x yedoenins 'Somei-yoshino' based on sequence analysis of PolA1 gene

open access: yesAdvances in Horticultural Science, 2015
Prunus × yedoensis ‘Somei-yoshino’ is the most popular cultivar of flowering cherry in Japan. Although the origin of this cultivar has been considered hybrid between P. pendula f. ascendens and P. lannesiana var. speciosa, the paternity of P.
I. Nakamura   +6 more
doaj   +1 more source

Testing robustness of relative complexity measure method constructing robust phylogenetic trees for Galanthus L. Using the relative complexity measure [PDF]

open access: yes, 2013
Background: Most phylogeny analysis methods based on molecular sequences use multiple alignment where the quality of the alignment, which is dependent on the alignment parameters, determines the accuracy of the resulting trees.
Sırrı Yüzbaşıoğlu   +25 more
core   +1 more source

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