Results 221 to 230 of about 5,976,385 (321)

Unraveling Synthetase's Mode of Action: The Pyrrolysyl‐tRNA Synthetase Dimer Uses Secondary Binding Sites in the Cell

open access: yesAngewandte Chemie International Edition, EarlyView.
The pyrrolysyl‐tRNA synthetase dimer exhibits an alternating mode of action of its monomers within its catalytic cycle, which is realized upon occupation of secondary binding sites located at the intermonomer interfaces outside the catalytic binding site.
Jessica Dröden   +6 more
wiley   +1 more source

When the Past Fades: Detecting Phylogenetic Signal with SatuTe. [PDF]

open access: yesMol Biol Evol
Manuel C   +5 more
europepmc   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

open access: yesAngewandte Chemie International Edition, EarlyView.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra   +10 more
wiley   +1 more source

Assessing the viability of genebanked seeds from rare, wild plants native to the United States using the D.E.A.D. paradigm

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Genebanks must maintain viable seeds for decades. Seeds that germinate are clearly alive, but some seeds, often from wild populations, do not germinate because they are dormant, empty, aged, or damaged (D.E.A.D.). This work evaluates the effects of D.E.A.D.
Christina Walters   +33 more
wiley   +1 more source

Detecting cryptic ghost lineage introgression in four‐taxon genomic datasets

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Hybridization and introgression are pervasive evolutionary forces that have played fundamental roles in shaping the diversity of wild and domesticated plants. Four‐taxon tests for introgression provide a reliable framework for detecting signatures of ancient introgression from genomic data, which have played an important role in ...
Evan S. Forsythe   +3 more
wiley   +1 more source

Quantitative assessment of masticatory muscles based on skull muscle attachment areas in Carnivora

open access: yesThe Anatomical Record, EarlyView.
Abstract Masticatory muscles are composed of the temporalis, masseter, and pterygoid muscles in mammals. Each muscle has a different origin on the skull and insertion on the mandible; thus, all masticatory muscles contract in different directions. Collecting in vivo data and directly measuring the masticatory muscles anatomically in various Carnivora ...
Kai Ito   +4 more
wiley   +1 more source

Cranial morphology reveals a lack of phylogenetic signal and rapid adaptive radiation in the bat genus Molossus (Chiroptera: Molossidae). [PDF]

open access: yesPLoS One
Olímpio APM   +9 more
europepmc   +1 more source

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