Results 31 to 40 of about 7,139,959 (205)

BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]

, 2009
A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ittzés, Péter, Jakó, Éena, Horváth, Arnold, Podani, János, Ari, Eszter   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Climate and species richness predict the phylogenetic structure of African mammal communities. [PDF]

PLoS ONE, 2015
We have little knowledge of how climatic variation (and by proxy, habitat variation) influences the phylogenetic structure of tropical communities.
Jason M Kamilar, Lydia Beaudrot, Kaye E Reed   +2 more
doaj   +1 more source

Phylogenetic relationships of Indian caecilians (Amphibia: Gymnophiona) inferred from mitochondrial rRNA gene sequences [PDF]

, 2002
India has a diverse caecilian fauna, including representatives of three of the six currently recognized families, the Caeciliidae, Ichthyophiidae, the endemic Uraeotyphlidae, but previous molecular phylogenetic studies of caecilians have not included ...
Oommen, O.V., Bernard L. Cohenb, Mark Wilkinson, Jonathan A. Sheps, Oommen V. Oommen, Wilkinson, M., Cohen, B.L., Sheps, J.A.   +7 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Environmental determinants of phylogenetic diversity in vernal pool habitats

Ecology and Evolution
Phylogenetic diversity offers critical insights into the ecological dynamics shaping species composition and ecosystem function, thereby informing conservation strategies.
Brandon Hendrickson
doaj   +1 more source

Intra- and interannual dynamics of grassland community phylogenetic structure are influenced by meteorological conditions before the growing season

Frontiers in Plant Science, 2022
The impact of global climate change on ecosystem structure has attracted much attention from researchers. However, how climate change and meteorological conditions influence community phylogenetic structure remains poorly understood. In this research, we
Lei Dong, Lei Dong, Ying Zheng, Ying Zheng, Jian Wang, Jian Wang, Jinrong Li, Jinrong Li, Zhiyong Li, Jinghui Zhang, Lixin Wang, Bailing Miao, Cunzhu Liang   +12 more
doaj   +1 more source

Phylogenetic support values are not necessarily informative : the case of the Serialia hypothesis (a mollusk phylogeny) [PDF]

, 2009
Background: Molecular phylogenies are being published increasingly and many biologists rely on the most recent topologies. However, different phylogenetic trees often contain conflicting results and contradict significant background data. Not knowing how
Annette Klussmann-Kolb, Christoph Mayer, Wägele, Johann Wolfgang, Klussmann-Kolb Annette, Heike Wägele, Mayer, Christoph, Wägele, Heike, Wägele J Wolfgang, Letsch, Harald, Mayer Christoph, Klussmann-Kolb, Annette, Misof Bernhard, Wägele Heike, Bernhard Misof, J Wolfgang Wägele, Harald Letsch, Misof, Bernhard, Letsch Harald   +17 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source