Results 211 to 220 of about 2,043,845 (347)

A Drosophila model of prion disease and its metabolic changes in the brain

Animal Models and Experimental Medicine, EarlyView.
We developed a Drosophila model for prion disease, and flies were capable of expressing the hamster prion protein (HaPrP) under the control of the GAL4/UAS system. The model exhibited some characteristics of the disease in mammals and displayed alterations in protein, sphingolipid, and carbohydrate metabolism. Preliminary applications have demonstrated
Dongdong Wang, Zhixin Sun, Pei Wen, Mengyang Zhao, Yuheng He, Fengting Gou, Jingjing Wang, Qing Fan, Xueyuan Li, Tianying Ma, Xiaoyu Wang, Wen Li, Sen Chen, Deming Zhao, Lifeng Yang   +14 more
wiley   +1 more source

A simple hierarchical model for heterogeneity in the evolutionary correlation on a phylogenetic tree. [PDF]

PeerJ, 2022
Revell LJ, Toyama KS, Mahler DL.
europepmc   +1 more source

Signatures of Random and Selective Mass Extinctions in Phylogenetic Tree Balance [PDF]

, 2002
Stephen B. Heard, Arne Ø. Mooers
openalex   +1 more source

From WGS to gels: Development and testing of PCR primers targeting toxic Digitalis in support of food safety

Applications in Plant Sciences, EarlyView.
Abstract Premise This study capitalized on a library of single‐nucleotide polymorphisms created via whole genome sequencing (WGS) to develop and test a PCR assay for detecting toxic Digitalis species in food products. Complex foods can be difficult to analyze, but safeguarding consumer well‐being and public health necessitates that products regulated ...
Elizabeth Sage Hunter, Sydnee Fo, Robert Literman, Richard H. Uva, Jennifer L. Wolny, Sara M. Handy   +5 more
wiley   +1 more source

Single-cell mutation calling and phylogenetic tree reconstruction with loss and recurrence. [PDF]

Bioinformatics, 2022
Kuipers J, Singer J, Beerenwinkel N.
europepmc   +1 more source

Detecting excess radical replacements in phylogenetic trees [PDF]

, 2003
Tal Pupko, Roded Sharan, Masami Hasegawa, Ron Shamir, Dan Graur   +4 more
openalex   +1 more source

Advancing phylogenomics in Amaranthaceae sensu stricto: Development and application of a new nuclear target enrichment bait set

Applications in Plant Sciences, EarlyView.
Abstract Premise Current phylogenies of Amaranthaceae sensu stricto (s.s.) are inadequately sampled and resolved to reflect the entire evolutionary history of the lineage, which is likely complex due to at least three whole‐genome duplication events, occasionally followed by subsequent additional polyploidization events and rapid diversification of ...
Tina Kiedaisch, Gudrun Kadereit, Anže Žerdoner Čalasan, Diego F. Morales‐Briones   +3 more
wiley   +1 more source

RAxML Grove: an empirical phylogenetic tree database. [PDF]

Bioinformatics, 2022
Höhler D, Pfeiffer W, Ioannidis V, Stockinger H, Stamatakis A.   +4 more
europepmc   +1 more source

Comparison of Three Methods for Estimating Internal Support on Phylogenetic Trees

, 2000
Mark E. Mort, Pamela S. Soltis, Pamela S. Soltis, Michelle L. Mabry   +3 more
openalex   +1 more source

Evolutionary models of phylogenetic trees [PDF]

, 2003
Iosif Pinelis
openalex   +1 more source