Results 291 to 300 of about 509,888 (322)

19 Dubious Ways to Compute the Marginal Likelihood of a Phylogenetic Tree Topology. [PDF]

open access: yesSyst Biol, 2020
Fourment M   +5 more
europepmc   +1 more source

A Bacterial Sulfotransferase Catalyzes an Unusual Di‐Sulfation in Natural Products Biosynthesis

open access: yesChemBioChem, EarlyView.
Herein, a unique sulfotransferase, AdpST, is identified from the adp biosynthetic gene clusters (BGC) in Streptomyces davaonensis DSM101723 and demonstrates that AdpST possesses di‐sulfation activity, which is unprecedented for bacterial phosphoadenosine‐5’‐phosphosulfate (PAPS)‐dependent sulfotransferases. It is further shown that the adp BGC contains
Conor Pulliam   +5 more
wiley   +1 more source

Exploring the Stability and Substrate Profile of Transaminase from Silicibacter pomeroyi with Ancestral Sequence Reconstruction

open access: yesChemBioChem, Accepted Article.
Amine transaminases (ATAs), belonging to the class III transaminases within the superfamily of pyridoxal‐5'‐phosphate (PLP)‐dependent enzymes, catalyze transamination reactions between amino donors and amino acceptors. These enzymes are particularly appealing for their role in the stereospecific synthesis of chiral amines.
Luyao Zhao   +4 more
wiley   +1 more source

Clade III Synthases Add Cyclic And Linear Terpenoids To The Psilocybe Metabolome

open access: yesChemBioChem, Accepted Article.
Psilocybe “magic mushrooms” are best known for their indolethylamine psilocybin, yet they encode enzymes for a much more diverse arsenal of small and potentially bioactive molecules. Here, we report on four Psilocybe cubensis clade III sesquiterpene synthases, CubB‐CubE, whose genes are differently expressed in fruiting bodies compared to vegetative ...
Nick Zschoche   +7 more
wiley   +1 more source

Actin Isovariant ACT2‐Mediated Cellular Auxin Homeostasis Regulates Lateral Root Organogenesis in Arabidopsis thaliana

open access: yesCytoskeleton, EarlyView.
ABSTRACT Lateral root (LR) organogenesis is regulated by cellular flux of auxin within pericycle cells, which depends on the membrane distribution and polar localization of auxin carrier proteins. The correct distribution of auxin carrier proteins relies on the intracellular trafficking of these proteins aided by filamentous actin as a track.
Aya Hanzawa   +2 more
wiley   +1 more source

Transforming a Historical Chemical Synthetic Route for Vanillin Starting from Renewable Eugenol to a Cell‐Free Bi‐Enzymatic Cascade

open access: yesChemSusChem, EarlyView.
An artificial enzymatic cascade to access natural vanillin from eugenol/clove oil was developed by revisiting the very first vanillin synthetic process from 19th century. The biosynthetic route consists of just two biocatalysts used as cell‐free preparation and molecular oxygen as oxidizing agent, outperforming also the natural microbial pathway which ...
Elisa Lanfranchi   +12 more
wiley   +1 more source

Interspecific comparisons of anuran embryonic epidermal landscapes and energetic trade‐offs in response to changes in salinity

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Freshwater salinization is an emerging stressor in amphibian populations, and embryonic stages are most vulnerable. To better understand the variation in embryonic osmoregulation, we challenged embryos of two phylogenetically diverse anuran species, Xenopus laevis and Lithobates (Rana) sylvaticus, along a gradient of non‐lethal ...
Kourtnie Whitfield, Erica J. Crespi
wiley   +1 more source

Phylogenetic tree constructing algorithms fit for grid computing with SVD

open access: green, 2006
Young Rock Kim   +3 more
openalex   +2 more sources

Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina   +12 more
wiley   +1 more source

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