Results 241 to 250 of about 2,045,161 (322)

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

PAML 4: phylogenetic analysis by maximum likelihood.

Molecular biology and evolution, 2007
Ziheng Yang
semanticscholar   +1 more source

An Idea to Explore: From How to Why: Using Evolutionary Biochemistry to Inspire Biochemistry Education

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Traditional biochemistry instruction often emphasizes mechanistic detail, that is, how molecules and pathways function, without equally addressing why they have their present forms. This fact‐centered approach can leave students overwhelmed and disconnected from the broader scientific narrative.
Alberto Vázquez‐Salazar
wiley   +1 more source

vSNP: a SNP pipeline for the generation of transparent SNP matrices and phylogenetic trees from whole genome sequencing data sets. [PDF]

BMC Genomics
Hicks J, Stuber T, Lantz K, Torchetti M, Robbe-Austerman S.   +4 more
europepmc   +1 more source

Geiger V2.0: an Expanded Suite of Methods for Fitting Macroevolutionary Models to Phylogenetic Trees

Bioinform., 2014
Matthew W. Pennell, J. Eastman, Graham J. Slater, Joseph W. Brown, J. Uyeda, R. FitzJohn, M. Alfaro, L. Harmon   +7 more
semanticscholar   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

NestedBD: Bayesian inference of phylogenetic trees from single-cell copy number profiles under a birth-death model. [PDF]

Algorithms Mol Biol
Liu Y, Edrisi M, Yan Z, A Ogilvie H, Nakhleh L.   +4 more
europepmc   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, EarlyView.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

RPANDA: an R package for macroevolutionary analyses on phylogenetic trees

, 2016
H. Morlon, E. Lewitus, F. Condamine, M. Manceau, J. Clavel, J. Drury   +5 more
semanticscholar   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source