Results 91 to 100 of about 175,417 (351)
Advanced Science, EarlyView.Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang +14 more
wiley +1 more source
Modeling the Ecology and Evolution of Biodiversity: Introduction to the Special Issue
Diversity, 2022 Applying relevant statistical models to empirical data analysis has been considered a very important procedure for scientists to answer research questions in the fields of biodiversity, phylogeography, evolutionary biology, paleoecology, phylogenetics ...
Dwueng-Chwuan Jhwueng
doaj +1 more source
Locating a Tree in a Phylogenetic Network in Quadratic Time [PDF]
, 2015 A fundamental problem in the study of phylogenetic networks is to determine whether or not a given phylogenetic network contains a given phylogenetic tree. We develop a quadratic-time algorithm for this problem for binary nearly-stable phylogenetic networks.
arxiv +1 more source
Exploring spaces of semi-directed phylogenetic networks [PDF]
arXiv, 2023 Semi-directed phylogenetic networks have recently emerged as a class of phylogenetic networks sitting between rooted (directed) and unrooted (undirected) phylogenetic networks as they contain both directed as well as undirected edges. While the spaces of rooted phylogenetic networks and unrooted phylogenetic networks have been analyzed in recent years ...
arxiv
The Phylogenetic Diversity of Metagenomes [PDF]
PLoS ONE, 2011 Phylogenetic diversity--patterns of phylogenetic relatedness among organisms in ecological communities--provides important insights into the mechanisms underlying community assembly. Studies that measure phylogenetic diversity in microbial communities have primarily been limited to a single marker gene approach, using the small subunit of the rRNA gene
Katherine S. Pollard +4 more
openaire +6 more sources
Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication
Advanced Science, EarlyView.Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He +6 more
wiley +1 more source
Advanced Science, EarlyView.Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao +15 more
wiley +1 more source
Two metrics for general phylogenetic networks [PDF]
arXiv, 2008 We prove that Nakhleh's latest dissimilarity measure for phylogenetic networks separates distinguishable phylogenetic networks, and that a slight modification of it provides a true distance on the class of all phylogenetic networks.
arxiv
Advanced Science, EarlyView.This study explores the structural heterogeneity and evolutionary adaptations of heteromultimeric bacterioferritins. Hetero‐Bfrs, evolved from either a homo‐Bfr or Ftn by gene duplications, differ from homo‐Bfrs substantially in the mechanisms underpinning iron oxidation and reduction despite high similarity in overall structure.
Yingxi Li +5 more
wiley +1 more source
Transforming phylogenetic networks: Moving beyond tree space [PDF]
arXiv, 2016 Phylogenetic networks are a generalization of phylogenetic trees that are used to represent reticulate evolution. Unrooted phylogenetic networks form a special class of such networks, which naturally generalize unrooted phylogenetic trees. In this paper we define two operations on unrooted phylogenetic networks, one of which is a generalization of the ...
arxiv