Results 291 to 300 of about 455,803 (329)

Enhancing capacities in genomic surveillance capabilities for SARS-CoV-2 and dengue virus: A South-South collaborative partnership. [PDF]

open access: yesPLOS Glob Public Health
Márquez S   +8 more
europepmc   +1 more source

Characterization of the Cubamyces Menziesii Terpenome

open access: yesChemBioChem, EarlyView.
The genome of Cubamyces menziesii reveals 18 putative sesquiterpene cyclase genes. These genes are cloned and expressed in Escherichia coli, yielding 10 active enzymes. Using farnesyl diphosphate as substrate, the enzymes are analyzed, and the products characterized after bioconversion, uncovering diverse sesquiterpene structures. This study highlights
Létitia Leydet   +10 more
wiley   +1 more source

A Bacterial Sulfotransferase Catalyzes an Unusual Di‐Sulfation in Natural Products Biosynthesis

open access: yesChemBioChem, EarlyView.
Herein, a unique sulfotransferase, AdpST, is identified from the adp biosynthetic gene clusters (BGC) in Streptomyces davaonensis DSM101723 and demonstrates that AdpST possesses di‐sulfation activity, which is unprecedented for bacterial phosphoadenosine‐5’‐phosphosulfate (PAPS)‐dependent sulfotransferases. It is further shown that the adp BGC contains
Conor Pulliam   +5 more
wiley   +1 more source

Solu: a cloud platform for real-time genomic pathogen surveillance. [PDF]

open access: yesBMC Bioinformatics
Saratto T   +5 more
europepmc   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

open access: yesChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout   +1 more
wiley   +1 more source

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

open access: yesChemBioChem, EarlyView.
This bacterial enzyme, cyclase‐phosphotriesterase (C‐PTE) from Ruegeria pomeroyi DSS‐3, shows significant potential for breaking down organophosphate pollutants. Beyond its capability to hydrolyze specific plasticizers such as triphenyl phosphate and tris(2‐chloropropyl) phosphate, C‐PTE's crystal structure reveals a binuclear zinc active site, and it ...
Dawei Ji   +5 more
wiley   +1 more source

Prevalence and genetic diversity of tick-borne encephalitis virus in ixodid ticks from specific regions of northwestern Russia. [PDF]

open access: yesPLoS One
Sharova AA   +22 more
europepmc   +1 more source

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