Results 211 to 220 of about 445,514 (353)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A review of the phylogeny of Palaearctic mealybugs (Hemiptera: Coccomorpha: Pseudococcidae)

, 2015
WOS: 000355781000009The mealybugs form the second largest family group within the scale insects (Hemiptera: Coccomorpha), with about 2,300 species in almost 300 genera, and is currently considered to include two families, Pseudococcidae and Rhizoecidae ...
Kaydan, Mehmet Bora, Kozar, Ferenc, Hodgson, Christopher   +2 more
core  

Reticulated adaptive radiation and phylogenomic diversity loss in the Hawaiian honeycreepers. [PDF]

Proc Natl Acad Sci U S A
Campana MG, Venkatraman MX, Tsuchiya MTN, Kearns AM, VanTassel NM, Henschen AE, Przelomska NAS, McInerney NR, Ochirbat ME, Lerner HRL, Callicrate TE, Hagemann M, Paxton EH, Cassin-Sackett L, James HF, Fleischer RC.   +15 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Expression of Concern: Structural and evolutionary constraints shape adaptive landscapes of immune-related genes across mammalian phylogeny. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Dolphyin: a combinatorial algorithm for identifying 1-Dollo phylogenies in cancer. [PDF]

Algorithms Mol Biol
Feng DW, El-Kebir M.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Chromsome Phylogeny [PDF]

Proceedings of the National Academy of Sciences, 1938
openaire   +2 more sources

Quantifying the predictability of evolution by analysis of coalescent rate variation. [PDF]

Mol Biol Evol
Volz E, Didelot X.
europepmc   +1 more source