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Mining an O-methyltransferase for de novo biosynthesis of physcion in Aspergillus nidulans

Applied Microbiology and Biotechnology, 2023
Physcion is one of natural anthraquinones, registered as a novel plant-derived fungicide due to its excellent prevention of plant disease. However, the current production of physcion via plant extraction limits its yield promotion and application.
Yongpeng Yao   +4 more
openaire   +3 more sources

Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics

Chemico-Biological Interactions, 2019
Anthraquinones constitute an important class of natural and synthetic compounds with a broad scope of pharmacological including anti-bacterial, antioxidant, laxative, anti-tumor and other activities. Physcion and physcion 8-O-β-glucopyranoside (PG) are common anthraquinones existed in various plants.
, XunLi   +7 more
openaire   +3 more sources

Unveiling esophageal cancer treatment mechanisms: network pharmacology and molecular docking of Physcion

Naunyn-Schmiedeberg's Archives of Pharmacology
This study investigates the effects of Physcion on esophageal cancer and its possible mechanisms of action. Potential Physcion targets were identified using databases. Transcriptomic data from 17 esophageal cancer and adjacent tissues were analyzed to find differentially expressed genes, intersecting with potential targets to select 16 key genes. Their
Guangbing, Hu   +6 more
openaire   +3 more sources

Natural drug physcion encapsulated zeolitic imidazolate framework, and their application as antimicrobial agent

Colloids and Surfaces B: Biointerfaces, 2019
In this study, we have encapsulated natural physcion (PHY) drug loading into metal-organic frameworks MOFs, zeolitic imidazolate frameworks (ZIFs) through straight-forward nano-precipitation technique. The synthesized PHY@ZIF-8 indicated high drug loading encapsulation efficiency i.e. 88%, whereas, drug loading capacity was found to be 11.49%.
Najaf Ali, Soomro   +6 more
openaire   +3 more sources

Physcion prevents high-fat diet-induced endothelial dysfunction by inhibiting oxidative stress and endoplasmic reticulum stress pathways.

European Journal of Pharmacology, 2023
High-fat diet (HFD)-induced obesity leads endothelial dysfunction and contributes to cardiovascular diseases. Palmitic acid (PA), a free fatty acid, is the main component of dietary saturated fat.
Yu-hao Wang   +9 more
semanticscholar   +1 more source

Physcion and chitosan-Oligosaccharide (COS) synergistically improve the yield by enhancing photosynthetic efficiency and resilience in wheat (Triticum aestivum L.).

Plant physiology and biochemistry : PPB, 2023
As progressively increasing food safety concerns, diversified plant diseases and abiotic stresses, environmental-friendly bio-pesticides and bio-stimulants combinations may are likely to serve as a vital means of safeguarding green and sustainable food ...
Jingchong Li   +6 more
semanticscholar   +1 more source

A new polymorph of physcion

Acta Crystallographica Section C Crystal Structure Communications, 2012
The structure of the title compound, 7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione, C16H12O5, was originally reported by Ulickýet al.[Acta Cryst.(1991). C47, 1879–1881] in the space groupP212121[polymorph (Io)]. The new polymorph, (Im), crystallizes in the space groupP21/c.
Henning, Hopf   +4 more
openaire   +2 more sources

Determination of rhein and physcion in rhubarb by microchip capillary electrophoresis in mixed hydro-organic solvent combined with laser-induced fluorescence detection.

Journal of Separation Science, 2023
Microchip capillary electrophoresis in mixed hydro-organic solvent combined with laser-induced fluorescence detection was developed for the separation and detection of physcion and rhein in rhubarb.
S. Chen   +4 more
semanticscholar   +1 more source

Physcion-8-O-gentiobioside from Rhamnus virgata

Phytochemistry, 1984
Abstract A new anthraquinone diglucoside isolated from Rhamnus virgata has been shown to be physcion-8- O -β-gentiobioside on the basis of spectral and other evidence.
S.B. Kalidhar, Pushpa Sharma
openaire   +1 more source

Synergistic interaction of physcion and chrysophanol on plant powdery mildew

Pest Management Science, 2007
Abstract The extract of the plant Rheum officinale Baill, mainly containing the anthraquinones physcion and chrysophanol, is highly active against plant powdery mildew.
Xiaojun, Yang   +4 more
openaire   +2 more sources

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