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The Comparison of the Efficiency of Emodin and Aloe-Emodin in Photodynamic Therapy
International Journal of Molecular Sciences, 2022 Skin cancer (melanoma and non-melanoma) is the most frequent type of malignancy in the Caucasian population. Photodynamic therapy (PDT) as an interesting and unique strategy may potentially boost standard therapeutic approaches. In the present study, the potential of emodin and aloe-emodin as photosensitizers in photodynamic therapy has been ...
Marta Wozniak +2 more
exaly +4 more sources
Anticancer potential of emodin
BioMedicine (Taiwan, 2012 Traditional Chinese Medicine (TCM) is widely used in clinical research due to its low toxicity, low number of side effects, and low cost. Many components of common fruits and vegetables play well-documented roles as chemopreventive or chemotherapeutic agents that suppress tumorigenesis. Anthraquinones are commonly extracted from the Polygonaceae family
Jing-Gung Chung, Shu-Chun Hsu
exaly +3 more sources
Evaluation of the inhibitory effects of emodin on Neospora caninum invasion and proliferation in vitro [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceThe impact of neosporosis on the livestock industry has worsening each year. Globally, annual losses were estimated to exceed $2.4 billion, with abortion rates reaching up to 47 % in affected herds.
Feixue Liu +10 more
doaj +2 more sources
Emodin inhibits colon cancer tumor growth by suppressing tumor cell glycolysis through inhibition of NAT10-mediated PGK1 ac4C modification [PDF]
Frontiers in OncologyIntroductionInhibition of glycolysis represents a potent therapeutic approach for colon cancer. Emodin, a natural plant-derived compound with anticancer properties, has shown efficacy in cancer treatment.
Zhuoxin Wei, Zhuo Lv, Weimin Zhang
doaj +2 more sources
Frontiers in Pharmacology, 2021 Our previous study showed that emodin enema modulates gut microbiota and delays CKD progression. However, the poor solubility, limited colonic irrigation retention time, and inadequate colon adhesion of emodin hinder its clinical application.
Zhaoyu Lu +13 more
doaj +1 more source
BMC Cancer, 2022 Background Previous studies reported that emodin extracted from Rheum palmatum L. exerts antiproliferation and antimetastatic effects in a variety of human cancer types.
Binyu Qin +10 more
doaj +1 more source
Advances in the mechanism of emodin-induced hepatotoxicity
HeliyonEmodin is a naturally occurring anthraquinone derivative and serves as an active component in various traditional Chinese herbal medicines. It is widely known for its broad pharmacological effects, including anti-inflammatory, antioxidant, and anticancer
Yupeng Wang +3 more
doaj +3 more sources
Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein. [PDF]
PLoS ONE, 2017 Development of multidrug resistance (MDR) is a continuous clinical challenge partially due to the overexpression of P-glycoprotein (P-gp) for chronic myelogenous leukemia (CML) patients.
Hongping Min +9 more
doaj +1 more source
Marine Drugs, 2022 Emodin, a hydroxyanthraquinone derivative, has been used as medicine for more than 2000 years due to its extensive pharmacological activities. Large-scale production of emodin has been achieved by optimizing the fermentation conditions of marine-derived ...
Lizhi Gong +5 more
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Cancer Cell International, 2021 Background Non-small cell lung cancers (NSCLC) account for most cases of lung cancer. More effort is needed to research new drug and combination therapies for this disease. An anthraquinone derivative, emodin shows anticancer potency.
Mingzhu Li +5 more
doaj +1 more source