Results 11 to 20 of about 12,407 (222)

Bioconcentration and Metabolism of Emodin in Zebrafish Eleutheroembryos [PDF]

Frontiers in Pharmacology, 2017
Emodin is a major active anthraquinone of various herbal laxatives, which can exert many pharmacological effects. However, chronic use of anthranoid laxatives, even at low dosages, may cause melanosis coli (MC).
Jiefeng Chen, Shaodong Li, Mengping Liu, Christopher Wai Kei Lam, Zheng Li, Xinjun Xu, Zuanguang Chen, Wei Zhang, Meicun Yao   +8 more
doaj   +2 more sources

Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance

BMC Molecular and Cell Biology, 2023
Background Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action of wound healing is not fully understood.
Aysenur Gunaydin-Akyildiz, Rabia Sare Yanikoglu, Meltem Gulec, Gulbahar Ozge Alim-Toraman, Ebru Didem Kuran, Sezen Atasoy, Abdullah Olgun, Gulacti Topcu   +7 more
doaj   +2 more sources

Inflammatory Stress Potentiates Emodin-Induced Liver Injury in Rats

Frontiers in Pharmacology, 2015
Herbal medicines containing emodin, widely used for the treatment of hepatitis in clinic, have been reported with hepatotoxicity in individuals. A modest inflammatory stress potentiating liver injury has been linked to the idiosyncratic drug-induced ...
Can eTu, Dan eGao, Dan eGao, Xiao-fei eLi, Xiao-fei eLi, Chun-yu eLi, Chun-yu eLi, Rui-sheng eLi, Yan-ling eZhao, Na eLi, Ge-liu-chang eJia, Ge-liu-chang eJia, Jing-yao ePang, Jing-yao ePang, He-rong eCui, Zhi-jie eMa, Xiao-he eXiao, Jia-Bo eWang   +17 more
doaj   +2 more sources

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

Drug Design, Development and Therapy, 2018
Nianxiu Tian,1 Yanbin Gao,1 Xiaolei Wang,1 Xiaoming Wu,2 Dawei Zou,3 Zhiyao Zhu,3 ZheJi Han,1 Tao Wang,1 Yimin Shi1 1Department of Endocrinology, School of Traditional Chinese Medicine, Capital Medical University, Fengtai District, Beijing, China ...
Tian N, Gao Y, Wang X, Wu X, Zou D, Zhu Z, Han ZJ, Wang T, Shi Y   +8 more
doaj   +1 more source

Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis

Journal of Translational Medicine, 2019
Background Hypercoagulation and neutrophilia are described in several cancers, however, whether they are involved in lung carcinogenesis is currently unknown.
Zibo Li, Yukun Lin, Shuhui Zhang, Lin Zhou, Guixi Yan, Yuehua Wang, Mengdi Zhang, Mengqi Wang, Haihong Lin, Qiaozhen Tong, Yongjian Duan, Gangjun Du   +11 more
doaj   +2 more sources

Emodin as an Inhibitor of PRV Infection In Vitro and In Vivo

Molecules, 2023
Pseudorabies (PR) is an acute and severe infectious disease caused by pseudorabies virus (PRV). Once the virus infects pigs, it is difficult to eliminate, resulting in major economic losses to the global pig industry.
Xiaojing Cai, Zhiying Wang, Xiaocheng Li, Jing Zhang, Zhiyuan Ren, Yi Shao, Yongkang Xu, Yan Zhu   +7 more
doaj   +1 more source

Emodin exhibits anti-acne potential by inhibiting cell growth, lipogenesis, and inflammation in human SZ95 sebocytes

Scientific Reports, 2023
Emodin, a natural anthraquinone derivative, possesses anti-proliferative and anti-inflammatory properties in skin diseases. However, little information is available on the efficacy of emodin in treating acne vulgaris (acne).
Si Liu, Xiao-Hua Luo, Yu-Feng Liu, Christos C. Zouboulis, Ge Shi   +4 more
doaj   +1 more source

The In Vitro Anti-Parasitic Activities of Emodin toward Toxoplasma gondii

Pharmaceuticals, 2023
Currently, toxoplasmosis affects nearly one-third of the world’s population, but the available treatments have several limitations. This factor underscores the search for better therapy for toxoplasmosis.
Oluyomi Stephen Adeyemi, Kosei Ishii, Kentaro Kato   +2 more
doaj   +1 more source

Ueber Aloe‐Emodin und Frangula‐Emodin [PDF]

Archiv der Pharmazie, 1899
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openaire   +2 more sources

Antiviral Activities of Halogenated Emodin Derivatives against Human Coronavirus NL63 [PDF]

, 2021
The current COVID-19 outbreak has highlighted the need for the development of new vaccines and drugs to combat Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2). Recently, various drugs have been proposed as potentially effective against COVID-
Martina Avbelj, Avbelj, Martina, Durán Alonso, María Beatriz, María Beatriz Durán-Alonso, Iskra, Jernej, Banjanac, Mihailo, Mihailo Banjanac, Hrvoje Petković, Horvat, Monika, Monika Horvat, Jernej Iskra, Durán-Alonso, María Beatriz, Petković, Hrvoje   +12 more
core   +2 more sources