Results 1 to 10 of about 3,286 (156)

The Comparison of the Efficiency of Emodin and Aloe-Emodin in Photodynamic Therapy. [PDF]

Int J Mol Sci, 2022
Skin cancer (melanoma and non-melanoma) is the most frequent type of malignancy in the Caucasian population. Photodynamic therapy (PDT) as an interesting and unique strategy may potentially boost standard therapeutic approaches. In the present study, the potential of emodin and aloe-emodin as photosensitizers in photodynamic therapy has been ...
Nowak-Perlak M, Bromke MA, Ziółkowski P, Woźniak M.   +3 more
europepmc   +4 more sources

Therapeutic effect of sustained release of aloe emodin via novel grafted polymer in electrospun nanofiber membranes on peritendinous adhesions [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionTendon injuries are prevalent musculoskeletal conditions in clinical settings, affecting various regions such as the rotator cuff tendons, forearm flexor/extensor tendons, finger flexor tendons, and Achilles tendon.
Xinpeng Dong, Yuan Wang, Yi Li, Xin Wang, Qing Yu, Changhao Han, Jiayi Wang, Shen Liu, Jinglei Wu, Shenghe Liu   +9 more
doaj   +2 more sources

Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis. [PDF]

Int J Mol Sci, 2023
Sepsis remains a major challenge owing to its severe adverse effects and high mortality, against which specific pharmacological interventions with high efficacy are limited. Mitigation of hyperactive inflammatory responses is a key factor in enhancing the likelihood of survival in patients with sepsis.
Su J, Chen S, Xiao J, Feng Z, Hu S, Su Q, Chen Q, Chen D.   +7 more
europepmc   +3 more sources

Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance [PDF]

BMC Molecular and Cell Biology, 2023
Background Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action of wound healing is not fully understood.
Aysenur Gunaydin-Akyildiz, Rabia Sare Yanikoglu, Meltem Gulec, Gulbahar Ozge Alim-Toraman, Ebru Didem Kuran, Sezen Atasoy, Abdullah Olgun, Gulacti Topcu   +7 more
doaj   +2 more sources

Aloe emodin isolated from Cassiae semen upregulates IFITM1 to suppress hepatitis B virus replication via the interferon signaling pathway [PDF]

mSphere
The seeds of Cassia obtusifolia L. or Cassia tora L., known as Cassiae semen (juemingzi in Chinese), has been traditionally utilized for its hepatoprotective, lipid-lowering, anti-inflammatory, and immunomodulatory properties.
Xin Wen, Xincan Yu, Yuxin Hu, Jiamin Chen, Dongwei Zhang, Yalin Hou, Shui Liu, Xuemeng Shi, Jun Xu   +8 more
doaj   +2 more sources

In vitro and in vivo antileishmanial effects of aloe-emodin on Leishmania major

Journal of Traditional and Complementary Medicine, 2015
Cutaneous leishmaniasis is a common parasitic disease that is endemic in some parts of Iran. The drugs of choice used for leishmaniasis therapy are associated with a risk of recurrence and serious adverse effects.
Abdolhossein Dalimi, Mahdi Delavari, Fatemeh Ghaffarifar, Javid Sadraei   +3 more
doaj   +3 more sources

Aloe Emodin Alleviates Radiation‐Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption [PDF]

Advanced Science
Aloe emodin is an anthraquinone of traditional Chinese medicine monomer, which plays a protective action in cardiovascular diseases. However, the regulatory mechanisms of aloe emodin in the protection of radiation‐induced heart damage (RIHD) are unclear.
Fan Ouyang, Yaling Li, Haoming Wang, Xiangyang Liu, Xiaoli Tan, Genyuan Xie, Junfa Zeng, Gaofeng Zeng, Qiong Luo, Hong Zhou, Siming Chen, Kai Hou, Jinren Fang, Xia Zhang, Linlin Zhou, Yukun Li, Anbo Gao   +16 more
doaj   +2 more sources

The examination of in vitro photosensitizing efficacy of aloe-emodin loaded liposome following photodynamic therapy on melanoma cell lines [PDF]

Scientific Reports
This study focused on investigating the enhanced photoactive properties of liposomal aloe-emodin for photodynamic treatment (PDT). Aloe-emodin (A-E) was encapsulated in liposomes by using the copper ion gradient method.
Martyna Nowak-Perlak, Marta Olszowy, Piotr Kupczyk, Dorota Wrześniok, Magdalena Zaremba-Czogalla, Roksana Dębicka, Alicja Makarec, Jerzy Gubernator, Piotr Ziółkowski, Marta Woźniak   +9 more
doaj   +2 more sources

Peptide-Mediated Targeted Delivery of Aloe-Emodin as Anticancer Drug. [PDF]

Molecules, 2022
Breast cancer is one of the most diffuse cancers in the world and despite the availability of the different drugs employed against it, the need for new and particularly more specific molecules is ever growing. In this framework, natural products are increasingly assuming an important role as new anticancer drugs.
Stringaro A, Serra S, Gori A, Calcabrini A, Colone M, Dupuis ML, Spadaro F, Cecchetti S, Vitali A.   +8 more
europepmc   +5 more sources

Novel Aloe-Emodin Derivatives as Potential Anticancer Agents: Synthesis, Characterization and Cytotoxic Activity [PDF]

Molecules
The fusion of heterocycles onto an anthraquinone scaffold represents a promising strategy to optimize anticancer activity. This study has the aim to synthesize and characterize novel anthra[1,2-b]furan compounds based on the natural product aloe-emodin ...
Jeltzlin Semerel, Shuhe Zheng, Haoyue Hu, Yuyu Fang, Nigel John, Pedro Fardim, Wim Dehaen   +6 more
doaj   +2 more sources