Results 41 to 50 of about 5,366 (218)
Targeting Anthracycline-Resistant Tumor Cells with Synthetic Aloe-Emodin Glycosides [PDF]
ACS Medicinal Chemistry Letters, 2011 The cytotoxic activity of aloe-emodin (AE), a natural anthranoid that readily permeates anthracycline-resistant tumor cells, was improved by the attachment of an amino-sugar unit to its anthraquinone core. The new class of AE glycosides (AEGs) showed a significant improvement in cytotoxicity-up to more than 2 orders of magnitude greater than those of ...
Elinor, Breiner-Goldstein +8 more
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Biochemical and transcriptomic evaluation of the toxic effects of aloin contaminated agricultural soils on the earth worm Eisenia andrei. [PDF]
, 2018 In the present study, we investigated the response of oxidative stress markers and related gene expression in worms exposed to Aloe vera crude exudates (aloin) contaminated agricultural soils for 7 and 14 days.
Banni, M. (Mohamed) +3 more
core +1 more source
Viruses, 2021 Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe reproductive failure in sows and respiratory diseases in growing and finishing pigs and results in great economic losses to the swine industry.
Zhichao Xu +8 more
doaj +1 more source
Could we really use aloe vera food supplements to treat diabetes? Quality control issues [PDF]
, 2017 Diabetes UK has recently listed a number of herbs and spices that have been clinically shown to improve blood glucose control in type-2 diabetes patients and the diabetes high-risk group.
Habtemariam, Solomon
core +3 more sources
Aloe Emodin Reduces Phthiodiolone Dimycocerosate Potentiating Vancomycin Susceptibility on Mycobacteria [PDF]
Indian Journal of Microbiology, 2018 Treatment of tuberculosis still represent a major public health issue. The emergence of multi-and extensively-drug resistant (MDR and XDR) Mycobacterium tuberculosis clinical strains further pinpoint the urgent need for new anti-tuberculous drugs. We previously showed that vancomycin can target mycobacteria lacking cell wall integrity, especially those
Céline Rens +6 more
openaire +3 more sources
Cellular Physiology and Biochemistry, 2017 Background/Aims: Aloe-emodin (1,8-dihydroxy-3-hydroxymethyl-anthraquinone), an anthraquinone active compounds, is isolated from some traditional medicinal plants such as Rheum palmatum L. and Cassia occidentalis, which induce hepatotoxicity in rats.
Xiaoxv Dong +6 more
doaj +1 more source
Natural Anthraquinones as Promising MAPK3 Inhibitors for Complementary Cancer Therapy
Journal of Chemistry, 2023 Objective. MAPK3 activates several nuclear transcription factors, including c-Jun and c-fos, by phosphorylating its downstream cytoplasmic protein, thereby contributing to cell proliferation and survival.
Samaneh Vaziri-Amjad +2 more
doaj +1 more source
Natural Compounds as Regulators of NLRP3 Inflammasome-Mediated IL-1[béta] Production [PDF]
, 2018 K
Benkő, Szilvia, Tőzsér, József
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Interaction of aloe-emodin with human serum albumin
Chinese Science Bulletin, 2007 The presence of several high affinity binding sites on human serum albumin (HSA) makes it a possible target for many drugs. This study is designed to examine the effect of aloe-emodin on HSA by fluorescence, CD spectroscopy and molecular modeling. The results of fluorescence measurements suggested that the hydrophobic interaction was the predominant ...
JinFeng Du +3 more
openaire +1 more source
Natural Product Communications, 2017 A high performance thin layer chromatographic (HPTLC) method was developed and validated for simultaneous determination of rhein and aloe-emodin, major anthraquinone constituents, in S. alata leaves.
Savita Chewchinda, Pongtip Sithisarn
doaj +1 more source