Results 1 to 10 of about 3,306 (168)

The Comparison of the Efficiency of Emodin and Aloe-Emodin in Photodynamic Therapy [PDF]

International Journal of Molecular Sciences, 2022
Skin cancer (melanoma and non-melanoma) is the most frequent type of malignancy in the Caucasian population. Photodynamic therapy (PDT) as an interesting and unique strategy may potentially boost standard therapeutic approaches. In the present study, the potential of emodin and aloe-emodin as photosensitizers in photodynamic therapy has been ...
Marta Wozniak, Mariusz A Bromke, Piotr Ziolkowski   +2 more
exaly   +5 more sources

Aloe-Emodin Induces Mitochondrial Dysfunction and Pyroptosis by Activation of the Caspase-9/3/Gasdermin E Axis in HeLa Cells

Frontiers in Pharmacology, 2022
Aloe-emodin (1,8-dihydroxy-3-hydroxymethyl-anthraquinone), derived from some Chinese edible medicinal herbs, exerts a potential anticancer activity on various cancer cells, making it a drug candidate for cancer therapy.
Kun Meng, Maojun Di, Liuliu Shi
exaly   +3 more sources

Therapeutic effect of sustained release of aloe emodin via novel grafted polymer in electrospun nanofiber membranes on peritendinous adhesions. [PDF]

Front Bioeng Biotechnol
IntroductionTendon injuries are prevalent musculoskeletal conditions in clinical settings, affecting various regions such as the rotator cuff tendons, forearm flexor/extensor tendons, finger flexor tendons, and Achilles tendon.
Dong X, Wang Y, Li Y, Wang X, Yu Q, Han C, Wang J, Liu S, Wu J, Liu S.   +9 more
europepmc   +2 more sources

Aloe emodin isolated from <i>Cassiae</i> semen upregulates IFITM1 to suppress hepatitis B virus replication via the interferon signaling pathway. [PDF]

mSphere
The seeds of Cassia obtusifolia L. or Cassia tora L., known as Cassiae semen (juemingzi in Chinese), has been traditionally utilized for its hepatoprotective, lipid-lowering, anti-inflammatory, and immunomodulatory properties.
Wen X, Yu X, Hu Y, Chen J, Zhang D, Hou Y, Liu S, Shi X, Xu J.   +8 more
europepmc   +2 more sources

Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance. [PDF]

BMC Mol Cell Biol, 2023
Background Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action of wound healing is not fully understood.
Gunaydin-Akyildiz A, Yanikoglu RS, Gulec M, Alim-Toraman GO, Kuran ED, Atasoy S, Olgun A, Topcu G.   +7 more
europepmc   +2 more sources

Combination of aloe emodin, emodin, and rhein from Aloe with EDTA sensitizes the resistant Acinetobacter baumannii to polymyxins. [PDF]

Front Cell Infect Microbiol
BackgroundThe continuous emergence and spread of polymyxin-resistant Acinetobacter baumannii pose a significant global health challenge, necessitating the development of novel therapeutic strategies. Aloe, with its long-standing history of medicinal use, has recently been the subject of substantial research for its efficacy against pathogenic ...
Zhao Y, Zhang T, Liang Y, Xie X, Pan H, Cao M, Wang S, Wu D, Wang J, Wang C, Hu W.   +10 more
europepmc   +4 more sources

In vitro studies on the photobiological properties of aloe emodin and aloin A [PDF]

Free Radical Biology and Medicine, 2003
Plants containing aloin A, aloe emodin, and structurally related anthraquinones have long been used as traditional medicines and in the formulation of retail products such as laxatives, dietary supplements, and cosmetics. Since a recent study indicated that topically applied aloe emodin increases the sensitivity of skin to UV light, we examined the ...
Daniel E Falvey, Wayne G Wamer
exaly   +3 more sources

Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis. [PDF]

Int J Mol Sci, 2023
Sepsis remains a major challenge owing to its severe adverse effects and high mortality, against which specific pharmacological interventions with high efficacy are limited. Mitigation of hyperactive inflammatory responses is a key factor in enhancing the likelihood of survival in patients with sepsis.
Su J, Chen S, Xiao J, Feng Z, Hu S, Su Q, Chen Q, Chen D.   +7 more
europepmc   +3 more sources

The examination of in vitro photosensitizing efficacy of aloe-emodin loaded liposome following photodynamic therapy on melanoma cell lines. [PDF]

Sci Rep
This study focused on investigating the enhanced photoactive properties of liposomal aloe-emodin for photodynamic treatment (PDT). Aloe-emodin (A-E) was encapsulated in liposomes by using the copper ion gradient method.
Nowak-Perlak M, Olszowy M, Kupczyk P, Wrześniok D, Zaremba-Czogalla M, Dębicka R, Makarec A, Gubernator J, Ziółkowski P, Woźniak M.   +9 more
europepmc   +2 more sources

Aloe Emodin Alleviates Radiation-Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption. [PDF]

Adv Sci (Weinh)
Aloe emodin is an anthraquinone of traditional Chinese medicine monomer, which plays a protective action in cardiovascular diseases. However, the regulatory mechanisms of aloe emodin in the protection of radiation‐induced heart damage (RIHD) are unclear.
Ouyang F, Li Y, Wang H, Liu X, Tan X, Xie G, Zeng J, Zeng G, Luo Q, Zhou H, Chen S, Hou K, Fang J, Zhang X, Zhou L, Li Y, Gao A.   +16 more
europepmc   +2 more sources