Results 11 to 20 of about 6,403 (242)

Aloe Emodin Alleviates Radiation‐Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption [PDF]

Advanced Science
Aloe emodin is an anthraquinone of traditional Chinese medicine monomer, which plays a protective action in cardiovascular diseases. However, the regulatory mechanisms of aloe emodin in the protection of radiation‐induced heart damage (RIHD) are unclear.
Fan Ouyang, Yaling Li, Haoming Wang, Xiangyang Liu, Xiaoli Tan, Genyuan Xie, Junfa Zeng, Gaofeng Zeng, Qiong Luo, Hong Zhou, Siming Chen, Kai Hou, Jinren Fang, Xia Zhang, Linlin Zhou, Yukun Li, Anbo Gao   +16 more
doaj   +3 more sources

Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance [PDF]

BMC Molecular and Cell Biology, 2023
Background Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action of wound healing is not fully understood.
Aysenur Gunaydin-Akyildiz, Rabia Sare Yanikoglu, Meltem Gulec, Gulbahar Ozge Alim-Toraman, Ebru Didem Kuran, Sezen Atasoy, Abdullah Olgun, Gulacti Topcu   +7 more
doaj   +2 more sources

Development of a Colloidal Gold Immunochromatographic Strip for the One-Step Evaluation of the Total Content of Rhein and Aloe-Emodin in Rhubarb [PDF]

International Journal of Analytical Chemistry, 2022
In this study, a colloidal gold immunochromatographic strip was developed for simultaneous detection of rhein and aloe-emodin in rhubarb. The cutoff value, defined as the lowest concentration for which the test line was invisible on the strip, was 50 ng ...
Ping Sun, Xin-Peng Li, Jie Xin, Tao Xue, Bo Zhang, Yan-Juan Liu   +5 more
doaj   +2 more sources

Combination of aloe emodin, emodin, and rhein from Aloe with EDTA sensitizes the resistant Acinetobacter baumannii to polymyxins. [PDF]

Front Cell Infect Microbiol
BackgroundThe continuous emergence and spread of polymyxin-resistant Acinetobacter baumannii pose a significant global health challenge, necessitating the development of novel therapeutic strategies. Aloe, with its long-standing history of medicinal use, has recently been the subject of substantial research for its efficacy against pathogenic ...
Zhao Y, Zhang T, Liang Y, Xie X, Pan H, Cao M, Wang S, Wu D, Wang J, Wang C, Hu W.   +10 more
europepmc   +4 more sources

Aloe emodin disrupts Candida albicans mitochondrial iron homeostasis against its hyphal development and oral candidiasis [PDF]

Applied Microbiology and Biotechnology
Candida albicans, a critical pathogen listed on the WHO fungal priority pathogens list, is a major cause of candidiasis and candidemia, particularly in immunocompromised populations.
Jiawei Shen, Chuanli Zhang, Yifan Lin, Chunfei Zhang, Jingzhi Zhou, Yujie Zhou, Lichen Gou, Ga Liao, Zhuoli Zhu, Lei Cheng, Binyou Liao, Biao Ren   +11 more
doaj   +2 more sources

Therapeutic effect of sustained release of aloe emodin via novel grafted polymer in electrospun nanofiber membranes on peritendinous adhesions [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionTendon injuries are prevalent musculoskeletal conditions in clinical settings, affecting various regions such as the rotator cuff tendons, forearm flexor/extensor tendons, finger flexor tendons, and Achilles tendon.
Xinpeng Dong, Yuan Wang, Yi Li, Xin Wang, Qing Yu, Changhao Han, Jiayi Wang, Shen Liu, Jinglei Wu, Shenghe Liu   +9 more
doaj   +2 more sources

Emodin and Aloe-Emodin Reduce Cell Growth and Disrupt Metabolic Plasticity in Human Melanoma Cells. [PDF]

Nutrients
Background/Objectives: Melanoma is an aggressive skin cancer with intratumor metabolic heterogeneity, which drives its progression and therapy resistance. Natural anthraquinones, such as emodin and aloe-emodin, exhibit anti-cancer properties, but their effects on metabolic plasticity remain unclear.
Baldassari F, Bonanomi M, Mallia S, Bonas M, Brivio E, Aramini T, Porro D, Gaglio D.   +7 more
europepmc   +4 more sources

Cell Metabolomics Reveals the Potential Mechanism of Aloe Emodin and Emodin Inhibiting Breast Cancer Metastasis. [PDF]

Int J Mol Sci, 2022
Metastasis is one of the main obstacles for the treatment and prognosis of breast cancer. In this study, the effects and possible mechanisms of aloe emodin (AE) and emodin (EMD) for inhibiting breast cancer metastasis were investigated via cell metabolomics.
Cheng G, Liu Z, Zheng Z, Song F, Zhuang X, Liu S.   +5 more
europepmc   +3 more sources

Aloe-Emodin Derivative, an Anthraquinone Compound, Attenuates Pyroptosis by Targeting NLRP3 Inflammasome in Diabetic Cardiomyopathy. [PDF]

Pharmaceuticals (Basel), 2023
Hu Y, Zhang S, Lou H, Mikaye MS, Xu R, Meng Z, Du M, Tang P, Chen Z, Chen Y, Liu X, Du Z, Zhang Y.   +12 more
europepmc   +3 more sources

Aloe-emodin as drug candidate for cancer therapy

Oncotarget, 2018
As a leading cause of global mortality, cancer frequently cannot be cured due to the development of drug resistance. Therefore, novel drugs are required. Naturally occurring anthraquinones are mostly present in Rumex and Rhamnus species and are of interest because of their structural similarity to anthracyclines as well established anticancer drugs. In
Nadire Özenver, Mohamed E.M. Saeed, L. Ömür Demirezer, Thomas Efferth   +3 more
openalex   +4 more sources