Results 41 to 50 of about 24,353 (197)
Journal of Food and Drug Analysis, 2020 Activated murine macrophages produce high level of nitric oxide by inducible nitric oxide synthase (iNOS), which is an important mechanism in macrophage-induced inflammation. In the present study, we isolated emodin, aloe-emodin and barbaloin compounds from Aloe barbadensis and investigated their inhibitory effects on the production of nitric oxide (NO)
M. Vanisree +3 more
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Synthesis and Anti-tumor Activity Evaluation of Rhein-Aloe Emodin Hybrid Molecule
Natural Product Communications, 2012 To improve the anti-tumor effects of rhein and aloe-emodin, a rhein-aloe-emodin hybrid molecule (RH-AE) was synthesized from rhein and aloe-emodin in the presence of dicyclohexylcarbodiimide (DCC) and 4-dimethylaminopyridine (DMAP).
Ye-fei Yuan +3 more
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Effects of Aloe-emodin and Emodin on Proliferation of the MKN45 Human Gastric Cancer Cell Line [PDF]
Asian Pacific Journal of Cancer Prevention, 2015 Aloe-emodin (1, 8-dihydroxy-3-hydroxyl-methylanthraquinone; AE) and emodin (1,3,8-trihydroxy-6- methylanthraquinone; EM) are anthraquinone derivatives that have been detected in some medical plants and share similar anthraquinone structures. AE and EM have been shown to exhibit anticancer activities in various cancer cell lines; however, the inhibitory
Takeshi, Chihara +6 more
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Anti-Inflammatory and Antiarthritic Activity of Anthraquinone Derivatives in Rodents
International Journal of Inflammation, 2014 Aloe emodin is isolated compound of aloe vera which is used traditionally as an anti-inflammatory agent. In vitro pharmacokinetic data suggest that glucuronosyl or sulfated forms of aloe emodin may provide some limitations in its absorption capacity ...
Ajay D. Kshirsagar +4 more
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Natural Anthraquinones as Promising MAPK3 Inhibitors for Complementary Cancer Therapy
Journal of Chemistry, 2023 Objective. MAPK3 activates several nuclear transcription factors, including c-Jun and c-fos, by phosphorylating its downstream cytoplasmic protein, thereby contributing to cell proliferation and survival.
Samaneh Vaziri-Amjad +2 more
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Journal of Pharmacy and Pharmacology, 1963 Abstract Barbaloin can be quantitatively converted into aloe-emodin by heating a solution in 4 N hydrochloric acid, containing 4 per cent ferric chloride, for 4 hr. in a boiling water bath under reflux. Each of these numerical conditions can be varied ±10 per cent without significantly altering the yields.
J W, FAIRBAIRN, S, SIMIC
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Natural Product Communications, 2017 A high performance thin layer chromatographic (HPTLC) method was developed and validated for simultaneous determination of rhein and aloe-emodin, major anthraquinone constituents, in S. alata leaves.
Savita Chewchinda, Pongtip Sithisarn
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Cellular Physiology and Biochemistry, 2017 Background/Aims: Aloe-emodin (1,8-dihydroxy-3-hydroxymethyl-anthraquinone), an anthraquinone active compounds, is isolated from some traditional medicinal plants such as Rheum palmatum L. and Cassia occidentalis, which induce hepatotoxicity in rats.
Xiaoxv Dong +6 more
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Viruses, 2021 Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe reproductive failure in sows and respiratory diseases in growing and finishing pigs and results in great economic losses to the swine industry.
Zhichao Xu +8 more
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Phytotherapy Research, EarlyView.ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source