Results 61 to 70 of about 6,403 (242)

Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy [PDF]

, 2014
published_or_final_versio
CHEUNG, F, Feng, Y, Kobayashi, S, Li, C, TAN, HY, Wang, N, Wang, X, Zhong, S   +7 more
core   +3 more sources

Induction of Apoptosis in HepaRG Cell Line by Aloe-Emodin through Generation of Reactive Oxygen Species and the Mitochondrial Pathway

Cellular Physiology and Biochemistry, 2017
Background/Aims: Aloe-emodin (1,8-dihydroxy-3-hydroxymethyl-anthraquinone), an anthraquinone active compounds, is isolated from some traditional medicinal plants such as Rheum palmatum L. and Cassia occidentalis, which induce hepatotoxicity in rats.
Xiaoxv Dong, Jing Fu, Xingbin Yin, Changhai Qu, Chunjing Yang, Huyiligeqi He, Jian Ni   +6 more
doaj   +1 more source

Natural Anthraquinones as Promising MAPK3 Inhibitors for Complementary Cancer Therapy

Journal of Chemistry, 2023
Objective. MAPK3 activates several nuclear transcription factors, including c-Jun and c-fos, by phosphorylating its downstream cytoplasmic protein, thereby contributing to cell proliferation and survival.
Samaneh Vaziri-Amjad, Massoud Moradi-Najmi, Amir Taherkhani   +2 more
doaj   +1 more source

Antiviral activity of Aloe vera against herpes simplex virus type 2: An in vitro study [PDF]

, 2007
In this study we tested the antiviral activity of a crude hot glycerine extract of Aloe vera gel which was grown in Bushehr (Southwest of Iran) against HSV-2 replication in Vero cell line.
Abbas Zadeh, Moloud, Rastian, Zahra, Sartavi, Kohzad, Zandi, Keivan   +3 more
core   +1 more source

Simultaneous HPTLC Determination of Rhein and Aloe-emodin in Leaves from Thailand and their Commercial Products

Natural Product Communications, 2017
A high performance thin layer chromatographic (HPTLC) method was developed and validated for simultaneous determination of rhein and aloe-emodin, major anthraquinone constituents, in S. alata leaves.
Savita Chewchinda, Pongtip Sithisarn
doaj   +1 more source

Enhancement of anti-inflammatory activity of Aloe vera adventitious root extracts through the alteration of primary and secondary metabolites via salicylic acid elicitation. [PDF]

PLoS ONE, 2013
Aloe vera (Asphodeloideae) is a medicinal plant in which useful secondary metabolites are plentiful. Among the representative secondary metabolites of Aloe vera are the anthraquinones including aloe emodin and chrysophanol, which are tricyclic aromatic ...
Yun Sun Lee, Hyun Kyoung Ju, Yeon Jeong Kim, Tae-Gyu Lim, Md Romij Uddin, Yeon Bok Kim, Jin Hong Baek, Sung Won Kwon, Ki Won Lee, Hak Soo Seo, Sang Un Park, Tae-Jin Yang   +11 more
doaj   +1 more source

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma [PDF]

, 2013
10.1371/journal.pone.0057015PLoS ...
A Kumar, AE Proudfoot, Alan Prem Kumar, Aruljothi Subramaniam, AZ Fernandis, BA Teicher, C Tabolacci, D Bhandari, DX Nguyen, Ekambaram Perumal, F Huang, G He, G Lazennec, G Sethi, Gautam Sethi, H Kulbe, H Lin, H Liu, J Libura, J Vandercappellen, JL Benovic, K Subik, Kam M. Hui, Kanjoormana Aryan Manu, Kodappully Sivaraman Siveen, Kwan Man, Lina H. K. Lim, M Arya, M Kucia, ML Lin, Muthu K. Shanmugam, P Rajendran, P Staller, Pradeep Bist, Q Huang, QS Xia, Ramar Perumal Samy, RE Bachelder, S Singh, T Schioppa, Tina H. Ong, Y Li, Y Nasuhara, Z Xiang, ZL Xiang, ZL Xiang   +45 more
core   +4 more sources

Effect of Aloe emodin against Lead Induced Hepatotoxicity

International Journal of Pharmaceutical Sciences Review and Research, 2022
The liver is the critical organ. Long-term occupational or environmental exposure as well as excessive exposure to lead may cause severe hepatotoxic effects. The widespread use of lead has led to manifold rise in the occurrence of free lead in biological systems and the inert environment.
Ananya Bhattacharjee, Venkatrao H Kulkarni, Prasanna V Habbu   +2 more
openaire   +1 more source

Interaction of anthraquinones of Cassia occidentalis seeds with DNA and Glutathione

Toxicology Reports, 2018
Consumption of Cassia occidentalis (CO) seeds has been associated with the hepatomyoencephalopathy (HME) in children. Recently, we have characterized the toxic anthraquinones (AQs) such as Emodin, Rhein, Aloe-emodin, Chrysophanol and Physcion in CO seeds
Gati Krushna Panigrahi, Neeraj Verma, Nivedita Singh, Somya Asthana, Shailendra K. Gupta, Anurag Tripathi, Mukul Das   +6 more
doaj   +1 more source

Absence of genotoxicity of purified Aloe vera whole leaf dry juice as assessed by an in vitro mouse lymphoma tk assay and an in vivo comet assay in male F344 rats

Toxicology Reports, 2021
Hydroxyanthracene derivatives (HAD) are naturally present in the latex layer of Aloe vera leaf, predominantly as aloins A, B and aloe-emodin. HAD are typically removed from commercial ingestible aloe products through activated charcoal filtration ...
Jiang Hu, Mel Lloyd, Cheryl Hobbs, Peter Cox, Keith Burke, Gareth Pearce, Michael A. Streicker, Quanyin Gao, Vasilios Frankos   +8 more
doaj   +1 more source