Results 71 to 80 of about 24,353 (197)

Barbaloin Attenuates Cisplatin‐Induced Hippocampal Neurotoxicity by Suppressing Oxidative Stress, Neuroinflammation, and Apoptosis: In Vivo and In Silico Evidence

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Important Aloe vera phytonutrient, barbaloin, inhibits the neurotoxic effects of cisplatin on hippocampus, which involves reducing oxidative stress, neuroinflammation, and apoptosis, thereby restoring the balance of neurotransmitters and cognition. The generated docking structures with 100‐ns molecular dynamics simulations show stable energy‐minimized ...
Rahamat Unissa Syed, Rihab Akasha, Nancy Mohammad Elafandy, Sally Hassan Abobaker, Afrah Nashmi Al‐Shammari, Lama Abdullah Altwalah, Rawabi Mohammed Menwer Aldafeeri, Amira Ibrahim Mohammed Ahmed Alfaki, Mohd Sajjad Ahmad Khan, Ashgan A. Ahmed   +9 more
wiley   +1 more source

Recent Developments in Chemical Synthesis and Biological Activities of Aloe-Emodin Derivatives

Organics
Aloe-emodin is an anthraquinone with a wide range of medicinal applications, including anti-angiogenic, anticancer, antimicrobial, antiviral, anti-inflammatory, and antioxidant activities.
Jeltzlin Semerel, Nigel John, Pedro Fardim, Wim Dehaen   +3 more
doaj   +1 more source

Aloe-emodin is an interferon-inducing agent with antiviral activity against Japanese encephalitis virus and enterovirus 71 [PDF]

, 2010
[[abstract]]In this study, aloe-emodin was identified as a potential interferon (IFN)-inducer by screening compounds from Chinese herbal medicine. Aloe-emodin showed low cytotoxicity to human HL-CZ promonocyte cells and TE-671 medulloblastoma cells and ...
Lin, CW (Lin, Cheng-Wen); Wu, CF (Wu, Chia-Fang); Hsiao, NW (Hsiao, Nai-Wan); Chang, CY (Chang, Ching-Yao); Li, SW (Li, Shih-Wein); Wan, L (Wan, Lei); Lin, YJ (Lin, Ying-Ju); Lin, WY (Lin, Wei-Yong)
core  

Avaliação dos efeitos de aloe-emodin em células uroteliais imortalizadas e neoplásicas cultivadas in vitro

, 2013
Aloe vera (Aloe barbadensis Miller), popularly known in Brazil as babosa, has a long history of use as medicinal plant for different therapeutic purposes.
Naves, Marina Araújo
core   +3 more sources

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

Food Safety and Health, Volume 4, Issue 3, Page 574-599, July 2026.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna, Hemant Sharma, Sonam Verma, Amar Jeet, Sumit Kumar Singh, Sharad Kumar Tripathi, Vedpriya Arya   +6 more
wiley   +1 more source

Safety of hydroxyanthracene derivatives for use in food

EFSA Journal, 2018
The Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the safety of hydroxyanthracene derivatives and to provide advice on a daily intake that does not give rise to concerns about harmful ...
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert‐Remy, Gunter Georg Kuhnle, Claude Lambré, Jean‐Charles Leblanc, Inger Therese Lillegaard, Peter Moldeus, Alicja Mortensen, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens‐Berendsen, Rudolf Antonius Woutersen, Raul J Andrade, Cristina Fortes, Pasquale Mosesso, Patrizia Restani, Fabiola Pizzo, Camilla Smeraldi, Adamantia Papaioannou, Matthew Wright   +27 more
doaj   +1 more source

In-Silico UHPLC Method Optimization for Aglycones in the Herbal Laxatives Aloe barbadensis Mill., Cassia angustifolia Vahl Pods, Rhamnus frangula L. Bark, Rhamnus purshianus DC. Bark, and Rheum palmatum L. Roots

Molecules, 2017
For the European Pharmacopoeia (Ph. Eur.) herbal monograph draft of Cassia angustifolia Vahl. and Cassia senna L. leaves and pods, a safety limitation of aloe-emodin and rhein was proposed, due to toxicological concerns. A quantitative, analytical method
Nadja Meier, Beat Meier, Samuel Peter, Evelyn Wolfram   +3 more
doaj   +1 more source

Peer review of the pesticide risk assessment of the active substance Trichoderma atroviride 77B

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The conclusions of the EFSA following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State, the Netherlands, for the pesticide active substance Trichoderma atroviride 77B and the considerations as regards the inclusion of the substance in Annex IV of Regulation (EC) No 396/2005 ...
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Teresa Capilla Chavez, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Silvia Mazzega, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Rositsa Serafimova, Adriana Scattareggia Marchese, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza   +48 more
wiley   +1 more source

Peer review of the pesticide risk assessment of the active substance Trichoderma asperellum T34

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State Sweden and co‐rapporteur Member State Italy for the pesticide active substance Trichoderma asperellum T34 are reported. The context of the peer review was
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Silvia Mazzega, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Adriana Scattareggia Marchese, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza   +48 more
wiley   +1 more source