Results 51 to 60 of about 5,366 (218)

Enhancement of anti-inflammatory activity of Aloe vera adventitious root extracts through the alteration of primary and secondary metabolites via salicylic acid elicitation. [PDF]

PLoS ONE, 2013
Aloe vera (Asphodeloideae) is a medicinal plant in which useful secondary metabolites are plentiful. Among the representative secondary metabolites of Aloe vera are the anthraquinones including aloe emodin and chrysophanol, which are tricyclic aromatic ...
Yun Sun Lee, Hyun Kyoung Ju, Yeon Jeong Kim, Tae-Gyu Lim, Md Romij Uddin, Yeon Bok Kim, Jin Hong Baek, Sung Won Kwon, Ki Won Lee, Hak Soo Seo, Sang Un Park, Tae-Jin Yang   +11 more
doaj   +1 more source

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica [PDF]

, 2017
Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on ...
A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Saccani, A Schmieder, A Sica, A Sica, B Ruffell, B Shao, BB Aggarwal, BC Kennedy, BK Sekhon, C Jia, C Liu, C Steidl, CE Lewis, CK Mueller, Curzio Rüegg, D Ghosh, DM Mosser, E Bolli, E Schutyser, F Li, F Zhao, FO Martinez, FR Zhao, G Shu, G Solinas, H Diao, H Fritz, H Kurahara, H Kurahara, H Ouyang, H Wang, H Wang, H Zhang, H Zhao, HYT Nguyen, IA Schepetkin, J Cook, J Deng, J Ding, J Gao, J Li, J Li, J Li, J Rius, J Wang, J Yin, J Zhang, JB Mitchem, JW Pollard, JY Jang, JY Shin, Kun Zhou, L Bingle, L Sanchez-Martin, L Varinska, LI Partecke, Li-kang Sun, Lin Miao, M Egeblad, M Hong, M Ito, M Jinushi, M Pesic, MA Khan, Margaret Gebauer, Micheal O. Hottiger, ML Taddei, MR Galdiero, Muriel Cuendet, MY Kim, P Allavena, P Suboj, P Sun, P Yu, PS Kyrn, Q Dong, Q Lin, R Graziose, R Noy, R Ostuni, R Zhu, S Banerjee, S Gao, S Iwanowycz, S Lunardi, S Shi, S Shimura, S Ye, SM Woo, SR Hingorani, SR Hyam, T Kawanishi, T Xu, V Riabov, W Lam, W Shi, Wei-ling Pu, X Jia, X Li, X Lin, X Nie, X Qian, X Sun, X Tang, X Wang, X Zhan, X Zhang, X Zhang, Xiu-mei Gao, XL Zhu, XW Yang, Y Cai, Y Kimura, Y Lei, Y Liu, Y Song, Y Tu, Y Wang, Y Wang, Y Zhao, YP Guo, Yun-sha Zhang, Z Cai, Z Jiang, Z Lin, Z Liu   +131 more
core   +1 more source

Interaction of anthraquinones of Cassia occidentalis seeds with DNA and Glutathione

Toxicology Reports, 2018
Consumption of Cassia occidentalis (CO) seeds has been associated with the hepatomyoencephalopathy (HME) in children. Recently, we have characterized the toxic anthraquinones (AQs) such as Emodin, Rhein, Aloe-emodin, Chrysophanol and Physcion in CO seeds
Gati Krushna Panigrahi, Neeraj Verma, Nivedita Singh, Somya Asthana, Shailendra K. Gupta, Anurag Tripathi, Mukul Das   +6 more
doaj   +1 more source

Absence of genotoxicity of purified Aloe vera whole leaf dry juice as assessed by an in vitro mouse lymphoma tk assay and an in vivo comet assay in male F344 rats

Toxicology Reports, 2021
Hydroxyanthracene derivatives (HAD) are naturally present in the latex layer of Aloe vera leaf, predominantly as aloins A, B and aloe-emodin. HAD are typically removed from commercial ingestible aloe products through activated charcoal filtration ...
Jiang Hu, Mel Lloyd, Cheryl Hobbs, Peter Cox, Keith Burke, Gareth Pearce, Michael A. Streicker, Quanyin Gao, Vasilios Frankos   +8 more
doaj   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao, Yuan Zong, Tao Wang, Jianan Li, Zengrong Ye, Famei Zhang, Guoying Zhou   +6 more
wiley   +1 more source

Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells [PDF]

, 2013
BACKGROUND: Multidrug resistance (MDR) is a major hurdle for cancer treatment worldwide and accounts for chemotherapy failure in over 90% of patients with metastatic cancer.
Armelle T Mbaveng, Benjamin Wiench, Igor K Voukeng, Roger Tsobou, Thomas Efferth, Veronique P Beng, Victor Kuete   +6 more
core   +1 more source

In Vitro Antitrypanosomal and Antibacterial Activity of Aqueous, Hydroethanolic and Ethanolic Extracts of Rumex obtusifolius L. Leaf and Root

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.
ABSTRACT Plant extracts are an important raw material for the development of new drugs. Rumex obtusifolius L., popularly known as ‘bitter dock’, has significant pharmacological properties. This study evaluated the in vitro antitrypanosomal activity of aqueous, hydroethanolic and ethanolic extracts from the leaf and roots of R. obtusifolius L.
Gabriela K. Borges, Gabriella B. Das Neves, Letícia Reichardt, Ubirajara Maciel da Costa, Luiz C. Miletti, Amanda L. Bastos‐Pereira   +5 more
wiley   +1 more source

Aloe vera–Based Green Synthesis of Silver Nanoparticles With Characterization, Potent Antibacterial and Antioxidant Properties

Asia-Pacific Journal of Chemical Engineering, Volume 21, Issue 2, March/April 2026.
ABSTRACT Green synthesis has emerged as a suitable alternative to the traditional method for manufacturing nanoparticles (NPs) as it provides a safer, sustainable, healthy, and environmental path for the NPs synthesis. Silver nanoparticles (AgNPs) were prepared using a green method with locally sourced Aloe vera leaf extract.
Janaki Baral, Sushant Timalsina, Sujan Dhungana, Laxmi Tiwari, Devendra Khadka, Bhoj Raj Poudel   +5 more
wiley   +1 more source

Allergic contact dermatitis to Aloe vera [PDF]

, 2007
We present the case of a 72-year-old woman observed for dermatitis on the legs followed by apperance of erythema on the eyelids. She had a past history of peripheral venous insufficiency and had been using self home-made Aloe vera juice over the legs for
Ferreira, M., Selores, M., Silva, E., Teixeira, M.   +3 more
core   +1 more source