Results 1 to 10 of about 183 (91)

Safety of hydroxyanthracene derivatives for use in food [PDF]

EFSA Journal, 2018
The Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the safety of hydroxyanthracene derivatives and to provide advice on a daily intake that does not give rise to concerns about harmful ...
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert‐Remy, Gunter Georg Kuhnle, Claude Lambré, Jean‐Charles Leblanc, Inger Therese Lillegaard, Peter Moldeus, Alicja Mortensen, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens‐Berendsen, Rudolf Antonius Woutersen, Raul J Andrade, Cristina Fortes, Pasquale Mosesso, Patrizia Restani, Fabiola Pizzo, Camilla Smeraldi, Adamantia Papaioannou, Matthew Wright   +27 more
doaj   +19 more sources

Development of an LC–DAD–MS-Based Method for the Analysis of Hydroxyanthracene Derivatives in Food Supplements and Plant Materials [PDF]

Molecules, 2022
Products based on plants containing hydroxyanthracene derivatives (HADs)—such as Rheum, Cassia, and Aloe species—are widely used in food supplements or nutraceuticals due to their laxative effects.
Francesca Loschi, Marta Faggian, Stefania Sut, Irene Ferrarese, Erica Maccari, Gregorio Peron, Stefano Dall’Acqua   +6 more
doaj   +7 more sources

Determination of 16 Hydroxyanthracene Derivatives in Food Supplements Using LC-MS/MS: Method Development and Application [PDF]

Toxins
Hydroxyanthracene derivatives (HADs) are plant substances produced by a variety of plant species, including different Aloe, Rheum, and Rhamnus species and Cassia senna. These plants are often used in food supplements to improve bowel function.
Svetlana V. Malysheva, Benoît Guillaume, Céline Vanhee, Julien Masquelier   +3 more
doaj   +6 more sources

UPLC-MS/MS Analysis of Hydroxyanthracene Derivatives in Botanical Food Products and Supplements: Surveillance of the Italian Market [PDF]

Foods
Hydroxyanthracene derivatives (HADs) are natural compounds that occur in several botanical species belonging to the genera Aloe L., Cassia L., Rheum L., Frangula Mill., and Rhamnus L.
Mariantonietta Peloso, Alessandro Capriotti, Damiano Accurso, Elena Butovskaya, Giorgio Fedrizzi, Elisabetta Caprai   +5 more
doaj   +6 more sources

Scientific Opinion on additional scientific data related to the safety of preparations of Rheum palmatum L., Rheum officinale Baill. and their hybrids, Rhamnus purshiana DC., Rhamnus frangula L. and Cassia senna L., submitted pursuant to Article 8(4) of Regulation (EC) No 1925/2006 [PDF]

EFSA Journal
The Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the safety of plant preparations from the root or rhizome of Rheum palmatum L., Rheum officinale Baill.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Helle Katrine Knutsen, Inge Mangelsdorf, Harry J. McArdle, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, AnnaMaria Rossi, Ariane Titz, Thibault Fiolet, Alexandre Maciuk   +18 more
doaj   +3 more sources

Absence of genotoxicity of purified Aloe vera whole leaf dry juice as assessed by an in vitro mouse lymphoma tk assay and an in vivo comet assay in male F344 rats [PDF]

Toxicology Reports, 2021
Hydroxyanthracene derivatives (HAD) are naturally present in the latex layer of Aloe vera leaf, predominantly as aloins A, B and aloe-emodin. HAD are typically removed from commercial ingestible aloe products through activated charcoal filtration ...
Jiang Hu, Mel Lloyd, Cheryl Hobbs, Peter Cox, Keith Burke, Gareth Pearce, Michael A. Streicker, Quanyin Gao, Vasilios Frankos   +8 more
doaj   +4 more sources

Lack of genotoxicity of rhubarb (rhizome) in the Ames and micronucleus in vitro tests [PDF]

Toxicology Reports, 2022
Hydroxyanthracene derivatives are widely distributed in the plant kingdom, mainly in botanicals such as the Hypericum, Rheum, Rhamnus and Aloe genera.
Gloria Melzi, Corrado L. Galli, Paola Ciliutti, Cristina Marabottini, Marina Marinovich   +4 more
doaj   +2 more sources

Lack of in vivo genotoxic effect of dried whole Aloe ferox juice [PDF]

Toxicology Reports, 2021
Aloe ferox Mill is widely used as a traditional herbal medicine for the treatment of a broad spectrum of illnesses given its laxative, anti-inflammatory, bitter tonic, anti-oxidant, antimicrobial and anti-cancer properties.Using the in vivo alkaline ...
Corrado L. Galli, Serena Cinelli, Paola Ciliutti, Gloria Melzi, Marina Marinovich   +4 more
doaj   +2 more sources

Untargeted Metabolomics for Profiling of Cascara, Senna, Rhubarb, and Frangula Metabolites [PDF]

Metabolites
Background/Objectives: Natural products containing hydroxyanthracene derivatives (HADs) such as Cascara (Rhamnus purshiana), Frangula (Rhamnus frangula), Rhubarb (Rheum palmatum), and Senna (Cassia angustifolia) have long been used for their laxative ...
Paola Nezi, Alessia Lucia Prete, Filippo Costanti, Vittoria Cicaloni, Mattia Cicogni, Laura Tinti, Laura Salvini, Monica Bianchini   +7 more
doaj   +2 more sources

Scientific Opinion on the substantiation of a health claim related to “Transitech®” and “improves transit and durably regulates it” pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2012
<p>Following an application from Vivatech submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies (NDA ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source