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Potential for Computational Genotoxicity: A Report on Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), 2024 [PDF]

Genes and Environment
Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), entitled “Potential for Computational Genotoxicity,” was held at Shujitsu University, Okayama, Japan, on December 8, 2024. The symposium discussed the
Naoki Koyama, Ayako Furuhama, Naomi L. Kruhlak, Nicolas Ken Shinada, Kazuki Izawa   +4 more
doaj   +2 more sources

Copper-Contaminated Substrate Biosorption by Penicillium sp. Isolated from Kefir Grains

Microorganisms, 2023
In this bioremediation study, the fungus Penicillium sp. isolated from kefir grains was evaluated for its resistance to copper in the culture medium. Penicillium sp. was cultivated in liquid medium prepared using 2% malt-agar at pH 7.0.
Antonio Ferreira de Oliveira, Raquellyne Baia Machado, Adriana Maciel Ferreira, Iracirema da Silva Sena, Maria Eduarda Silveira, Ana Maria Santos de Almeida, Francinaldo S. Braga, Alex Bruno Lobato Rodrigues, Roberto Messias Bezerra, Irlon Maciel Ferreira, Alexandro Cezar Florentino   +10 more
doaj   +1 more source

Direct and Indirect Genotoxicity of Graphene Family Nanomaterials on DNA—A Review

Nanomaterials, 2021
Graphene family nanomaterials (GFNs), including graphene, graphene oxide (GO), reduced graphene oxide (rGO), and graphene quantum dots (GQDs), have manifold potential applications, leading to the possibility of their release into environments and the ...
Kangying Wu, Qixing Zhou, Shaohu Ouyang
doaj   +1 more source

The Protective Effects of Carvacrol on Diphenhydramine-Induced Genotoxicity in Human Peripheral Blood Lymphocytes [PDF]

Research Journal of Pharmacognosy, 2021
Background and Objectives: Carvacrol is a natural antioxidant possessing various biological properties. Diphenhydramine is a first-generation antihistamine prescribed for allergies and the common cold.
Mehdi Evazalipour, Sana Moayedi, Pouya Safarzadeh Kozani, Pooria Safarzadeh Kozani, Ehsan Zamani*   +4 more
doaj   +1 more source

Genotoxicity evaluation of three anesthetics commonly employed in aquaculture using Oreochromis niloticus and Astyanax lacustris

Aquaculture Reports, 2020
The use of non-plant and plant-derived anesthetics in aquaculture activities is a frequent and necessary practice to maintain fish welfare. Currently anesthetics authorized for use in aquaculture activities are limited, and the use of unauthorized ...
Hélina dos Santos Nascimento, Bruno do Amaral Crispim, Luiza Flávia Veiga Francisco, Felipe Mendes Merey, Fábio Kummrow, Lucilene Finoto Viana, Luís Antonio Kioshi Aoki Inoue, Alexeia Barufatti   +7 more
doaj   +1 more source

Allelochemical Activity of Eugenol-Derived Coumarins on Lactuca sativa L.

Plants, 2020
Coumarins are widely distributed substances in plant species that promote phytotoxic effects, allowing them to be exploited as herbicides less harmful to the environment, since many invasive species have demonstrated resistance to commercially available ...
Kamilla Pacheco Govêa, Rafaella Sueko Tomita Pereira, Mateus Donizetti Oliveira de Assis, Pâmela Ingrid Alves, Guilherme Andrade Brancaglion, André Eidi Toyota, José Vaz Cardoso Machado, Diogo Teixeira Carvalho, Thiago Corrêa de Souza, Luiz Alberto Beijo, Luciene de Oliveira Ribeiro Trindade, Sandro Barbosa   +11 more
doaj   +1 more source

Comparative study on genotoxicity methods between OECD Test guidelines and GB15193

Zhongguo shipin weisheng zazhi, 2022
ObjectiveThe purpose of this study is to compare genotoxicity methods between OECD test guidelines and China food safety standards（GB15193）．MethodsMain parameters of related genotoxicity methods in OECD Testing Guidelines and GB 15193 standards were ...
ZHANG Xiaopeng, ZHAO Min, YU Zhou, JIA Xudong   +3 more
doaj   +1 more source

Considerations for the genotoxicity assessment of middle size peptide drugs containing non-canonical amino acid residues

Genes and Environment, 2023
Background Middle size peptides (MSPs) have emerged as a promising new pharmaceutical modality. We are seeking the best way to assess the non-clinical safety of MSPs. Consideration The requirements for assessing the genotoxicity of pharmaceuticals differ
Masayuki Mishima, Kei-ichi Sugiyama
doaj   +1 more source

Primary and Secondary Genotoxicity of Nanoparticles: Establishing a Co-Culture Protocol for Assessing Micronucleus Using Flow Cytometry

Frontiers in Toxicology, 2022
Genotoxicity is an important endpoint to assess for understanding the risks associated with nanoparticles (NPs). Most genotoxicity studies performed on NPs have focused on primary genotoxicity analyzed by comet- or micronuclei (MN) assay using ...
N. V. Srikanth Vallabani, Hanna L. Karlsson   +1 more
doaj   +1 more source

Thymoquinone ameliorates lead-induced suppression of the antioxidant system in rat kidneys

Libyan Journal of Medicine, 2016
Objective: Alteration of the antioxidant status in the kidneys may be related to lead (Pb) intoxication. The present study aimed to investigate the possible beneficial effect of thymoquinone (TQ), the major active ingredient of the volatile oil of ...
Aymen Mabrouk, Hassen Ben Cheikh
doaj   +1 more source