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Potential for Computational Genotoxicity: A Report on Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), 2024 [PDF]

Genes and Environment
Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), entitled “Potential for Computational Genotoxicity,” was held at Shujitsu University, Okayama, Japan, on December 8, 2024. The symposium discussed the
Naoki Koyama, Ayako Furuhama, Naomi L. Kruhlak, Nicolas Ken Shinada, Kazuki Izawa   +4 more
doaj   +2 more sources

Direct and Indirect Genotoxicity of Graphene Family Nanomaterials on DNA—A Review

Nanomaterials, 2021
Graphene family nanomaterials (GFNs), including graphene, graphene oxide (GO), reduced graphene oxide (rGO), and graphene quantum dots (GQDs), have manifold potential applications, leading to the possibility of their release into environments and the ...
Qixing Zhou, Shaohu Ouyang, Zhou Qixing   +2 more
exaly   +3 more sources

White phosphorus genotoxicity

BIO Web of Conferences, 2021
The genotoxicity of white phosphorus was previously evaluated using the Ames test, which demonstrated the absence of toxicity. However, with all the advantages of this method, the use of the Ames test has some shortfallsin assessing genotoxicity.
Mindubaev Anton, Babynin Edward, Minzanova Salima, Badeeva Elena, Akosah Yaw   +4 more
doaj   +2 more sources

Genotoxicity assessment of chemical mixtures [PDF]

EFSA Journal, 2019
The EFSA Scientific Committee addressed in this document the peculiarities related to the genotoxicity assessment of chemical mixtures. The EFSA Scientific Committee suggests that first a mixture should be chemically characterised as far as possible ...
EFSA Scientific Committee, Simon More, Vasileios Bampidis, Diane Benford, Jos Boesten, Claude Bragard, Thorhallur Halldorsson, Antonio Hernandez‐Jerez, Susanne Hougaard‐Bennekou, Kostas Koutsoumanis, Hanspeter Naegeli, Søren Saxmose Nielsen, Dieter Schrenk, Vittorio Silano, Dominique Turck, Maged Younes, Gabriele Aquilina, Riccardo Crebelli, Rainer Gürtler, Karen Ildico Hirsch‐Ernst, Pasquale Mosesso, Elsa Nielsen, Roland Solecki, Maria Carfì, Carla Martino, Daniela Maurici, Juan Parra Morte, Josef Schlatter   +27 more
doaj   +4 more sources

Common Considerations for Genotoxicity Assessment of Nanomaterials [PDF]

Frontiers in Toxicology, 2022
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk.
Rosalie K. Elespuru, Shareen H. Doak, Andrew R. Collins, Maria Dusinska, Stefan Pfuhler, Mugimane Manjanatha, Renato Cardoso, Connie L. Chen   +7 more
doaj   +2 more sources

Copper-Contaminated Substrate Biosorption by Penicillium sp. Isolated from Kefir Grains

Microorganisms, 2023
In this bioremediation study, the fungus Penicillium sp. isolated from kefir grains was evaluated for its resistance to copper in the culture medium. Penicillium sp. was cultivated in liquid medium prepared using 2% malt-agar at pH 7.0.
Antonio Ferreira de Oliveira, Raquellyne Baia Machado, Adriana Maciel Ferreira, Iracirema da Silva Sena, Maria Eduarda Silveira, Ana Maria Santos de Almeida, Francinaldo S. Braga, Alex Bruno Lobato Rodrigues, Roberto Messias Bezerra, Irlon Maciel Ferreira, Alexandro Cezar Florentino   +10 more
doaj   +1 more source

Genotoxicity of Aspartame [PDF]

Drug and Chemical Toxicology, 2004
In the present study, the genotoxic effects of the low-calorie sweetener aspartame (ASP), which is a dipeptide derivative, was investigated using chromosome aberration (CA) test, sister chromatid exchange (SCE) test, micronucleus test in human lymphocytes and also Ames/Salmonella/ microsome test.
Rencüzogullari E., Tüylü B.A., Topaktaş M., Ila H.B., Kayraldiz A., Arslan M., Diler S.B.   +6 more
openaire   +2 more sources

The Protective Effects of Carvacrol on Diphenhydramine-Induced Genotoxicity in Human Peripheral Blood Lymphocytes [PDF]

Research Journal of Pharmacognosy, 2021
Background and Objectives: Carvacrol is a natural antioxidant possessing various biological properties. Diphenhydramine is a first-generation antihistamine prescribed for allergies and the common cold.
Mehdi Evazalipour, Sana Moayedi, Pouya Safarzadeh Kozani, Pooria Safarzadeh Kozani, Ehsan Zamani*   +4 more
doaj   +1 more source

Genotoxicity evaluation of three anesthetics commonly employed in aquaculture using Oreochromis niloticus and Astyanax lacustris

Aquaculture Reports, 2020
The use of non-plant and plant-derived anesthetics in aquaculture activities is a frequent and necessary practice to maintain fish welfare. Currently anesthetics authorized for use in aquaculture activities are limited, and the use of unauthorized ...
Hélina dos Santos Nascimento, Bruno do Amaral Crispim, Luiza Flávia Veiga Francisco, Felipe Mendes Merey, Fábio Kummrow, Lucilene Finoto Viana, Luís Antonio Kioshi Aoki Inoue, Alexeia Barufatti   +7 more
doaj   +1 more source

Allelochemical Activity of Eugenol-Derived Coumarins on Lactuca sativa L.

Plants, 2020
Coumarins are widely distributed substances in plant species that promote phytotoxic effects, allowing them to be exploited as herbicides less harmful to the environment, since many invasive species have demonstrated resistance to commercially available ...
Kamilla Pacheco Govêa, Rafaella Sueko Tomita Pereira, Mateus Donizetti Oliveira de Assis, Pâmela Ingrid Alves, Guilherme Andrade Brancaglion, André Eidi Toyota, José Vaz Cardoso Machado, Diogo Teixeira Carvalho, Thiago Corrêa de Souza, Luiz Alberto Beijo, Luciene de Oliveira Ribeiro Trindade, Sandro Barbosa   +11 more
doaj   +1 more source