Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay.
PLoS ONE, 2023 Toxicity evaluation of engineered nanomaterials is challenging due to the ever increasing number of materials and because nanomaterials (NMs) frequently interfere with commonly used assays.
Maelle Fontaine +13 more
doaj +1 more source
Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]
, 2001 Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht +7 more
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Lead-induced DNA damage in Vicia faba root cells: Potential involvement of oxidative stress [PDF]
, 2011 Genotoxic effects of lead (0–20 µM) were investigated in whole-plant roots of Vicia faba L., grown hydroponically under controlled conditions. Lead-induced DNA damage in V.
Jean, Séverine +7 more
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The genotoxicity of caecal water from gilts following experimentally induced Fusarium mycotoxicosis
Veterinární Medicína, 2015 The examination of caecal contents allows one to investigate the exposure of colon mucosa to dietary toxins and the chemical contaminants present in animal feed.
A. Nowak +6 more
doaj +1 more source
Evaluation of genotoxicity induced by endodontic materials: A systematic review
Saudi Endodontic Journal, 2022 The ability of a substance to cause harm to the DNA molecule is known as genotoxicity. Because there is significant evidence of link between genetic damage and carcinogenesis, determining the real health hazards to patients and dental workers requires a ...
Sadaf Tamanna +3 more
doaj +1 more source
Assessment of the potential in vivo ecotoxicity of Double-Walled Carbon Nanotubes (DWNTs) in water, using the amphibian Ambystoma mexicanum [PDF]
, 2007 Because of their specific properties (mechanical, electrical, etc), carbon nanotubes (CNTs) are being assessed for inclusion in many manufactured products.
Flahaut, Emmanuel +4 more
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Thresholds of Genotoxic and Non-Genotoxic Carcinogens
Toxicological Research, 2018 Exposure to chemical agents is an inevitable consequence of modern society; some of these agents are hazardous to human health. The effects of chemical carcinogens are of great concern in many countries, and international organizations, such as the World Health Organization, have established guidelines for the regulation of these chemicals. Carcinogens
openaire +3 more sources
Mutagenic impact on fish of runoff events in agricultural areas in south-west France [PDF]
, 2011 When heavy rainfall follows herbicide application, the intense surface runoff causes stream water contamination. Aquatic organisms are then briefly exposed to a complex mixture of contaminants.
Pinelli, Eric +14 more
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Signs of deferasirox genotoxicity [PDF]
Cytotechnology, 2013 Iron overload is a major health problem for patients who have to have continuous blood transfusions. It brings some metabolic problems together. Various iron chelating agents are being used for treatment of hemochromatosis which arises from excess iron accumulation.
Ila, Hasan Basri +3 more
openaire +4 more sources
Investigating quantitative genotoxicity indicators by DFT analysis of TiO2 surface
, 2023 This dataset houses a research poster and its poster abstract. The set of documents was first presented at the doctoral days organized by the Doctoral Committee of the Nanoscience, Materials and Chemical Engineering program at Escuela Técnica Superior ...
Calatayud, Monica +4 more
core +1 more source