Results 11 to 20 of about 56,006 (307)

Genotoxicity of Silver Nanoparticles [PDF]

Nanomaterials, 2020
Silver nanoparticles (AgNPs) are widely used in diverse sectors such as medicine, food, cosmetics, household items, textiles and electronics. Given the extent of human exposure to AgNPs, information about the toxicological effects of such products is required to ensure their safety.
Adriana Rodriguez-Garraus, Amaya Azqueta, Ariane Vettorazzi, Adela López de Cerain   +3 more
openaire   +4 more sources

Comparative study on genotoxicity methods between OECD Test guidelines and GB15193

Zhongguo shipin weisheng zazhi, 2022
ObjectiveThe purpose of this study is to compare genotoxicity methods between OECD test guidelines and China food safety standards（GB15193）．MethodsMain parameters of related genotoxicity methods in OECD Testing Guidelines and GB 15193 standards were ...
ZHANG Xiaopeng, ZHAO Min, YU Zhou, JIA Xudong   +3 more
doaj   +1 more source

Considerations for the genotoxicity assessment of middle size peptide drugs containing non-canonical amino acid residues

Genes and Environment, 2023
Background Middle size peptides (MSPs) have emerged as a promising new pharmaceutical modality. We are seeking the best way to assess the non-clinical safety of MSPs. Consideration The requirements for assessing the genotoxicity of pharmaceuticals differ
Masayuki Mishima, Kei-ichi Sugiyama
doaj   +1 more source

Primary and Secondary Genotoxicity of Nanoparticles: Establishing a Co-Culture Protocol for Assessing Micronucleus Using Flow Cytometry

Frontiers in Toxicology, 2022
Genotoxicity is an important endpoint to assess for understanding the risks associated with nanoparticles (NPs). Most genotoxicity studies performed on NPs have focused on primary genotoxicity analyzed by comet- or micronuclei (MN) assay using ...
N. V. Srikanth Vallabani, Hanna L. Karlsson   +1 more
doaj   +1 more source

Lead-induced genotoxicity to Vicia faba L.roots in relation with metal cell uptake and initial speciation [PDF]

, 2011
Formation of organometallic complexes in soil solution strongly influence metals phytoavailability. However, only few studies deal with the influence of metalspeciation both on plant uptake and genotoxicity. In the present study, Viciafaba seedlings were
J. Silvestre, B. Pourrut, Silvestre, Jérôme, Pinelli, Eric, Dumat, Camille, C. Dumat, Shahid, Muhammad, Pourrut, Bertrand, E. Pinelli, M. Shahid   +9 more
core   +1 more source

Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]

, 2012
The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Khadra, Ahmed, A. Khadra, Hamdi, Hassan, Hafidi, Mohamed, Bousquet‐mélou, Alain, Pinelli, Eric, Merlina, Georges, Guiresse, Agnès Maritchù, HATIFI, Mohamed, H. Hamdi, M. Guiresse, Lacroix, Marlene Z., G. Merlina, HAMDI, H, M. Hafidi, E. Pinelli, Bousquet-Mélou, Alain, Lacroix, Marlène, M.Z. Lacroix, Guiresse, Maritxu, A. Bousquet-Melou   +20 more
core   +1 more source

Assessment of the genotoxicity of olive mill waste water (OMWW) with the Vicia faba micronucleus test [PDF]

, 2007
The present study concerns the genotoxicity of olive mill waste water (OMWW) generated in mills producing olive oil in Morocco. The Vicia faba micronucleus test was used to evaluate the genotoxicity of OMWW and the six major phenolic compounds identified
Hafidi, Mohamed, Revel, J.C., Pinelli, Eric, Merlina, Georges, El Hajjouji, Houda, Guiresse, Agnès Maritchù, Revel, Jean-Claude, Guiresse, Maritxu   +7 more
core   +1 more source

Thymoquinone ameliorates lead-induced suppression of the antioxidant system in rat kidneys

Libyan Journal of Medicine, 2016
Objective: Alteration of the antioxidant status in the kidneys may be related to lead (Pb) intoxication. The present study aimed to investigate the possible beneficial effect of thymoquinone (TQ), the major active ingredient of the volatile oil of ...
Aymen Mabrouk, Hassen Ben Cheikh
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 215 (FGE.215): Seven α,β-Unsaturated Cinnamyl Ketones from subgroup 3.2 of FGE.19 [PDF]

EFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of flavouring substances from subgroup 3.2 of FGE.19 in the Flavouring Group Evaluation ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 213, Revision 1 (FGE.213Rev1): Consideration of genotoxic potential for α,β-Unsaturated Alicyclic ketones and precursors from chemical subgroup 2.7 of FGE.19 [PDF]

EFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 26 flavouring substances from subgroup 2.7 of FGE.19 in the Flavouring Group ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source