Results 211 to 220 of about 4,321 (234)

Kobayashi's Aryne Precursor for the One-Step Synthesis of Anthraquinones and Its Application to the Total Synthesis of Chrysophanol, Danthron, and Physcion.

Journal of Organic Chemistry
A one-step synthetic method to access medicinally essential anthraquinones has been developed by reacting Kobayashi's aryne precursors with 3-sulfonylphthalides following [4 + 2] Hauser-Kraus annulation reaction. The developed method has been implemented
Sayantan Kundu, Sudip Mandal, B. Thirupathi   +2 more
semanticscholar   +1 more source

Biosynthesis of Physcion and Identification of an O-Methyltransferase with C6-OH Selectivity in Aspergillus chevalieri BYST01.

ACS Chemical Biology
Physcion, a polyketide natural product derived from plants and microorganisms, has been commercially approved as an agricultural fungicide for the prevention and treatment of powdery mildew.
Zhong-di Huang, Shu-Xiang Zhang, Ye Wang, Zhi-Wen Song, Wei-Yu Wang, Cai-Ping Yin, Yinglao Zhang   +6 more
semanticscholar   +1 more source

Antifungal Activity and Mechanism of Physcion against Sclerotium rolfsii, the Causal Agent of Peanut Southern Blight.

Journal of Agricultural and Food Chemistry
Peanut southern blight, caused by the soil-borne pathogen Sclerotium rolfsii, is a widespread and devastating epidemic. Frequently, it is laborious to effectively control by labor-intensive foliar sprays of agrochemicals due to untimely find.
Di Liu, Xuewei Mao, Guoyan Zhang, Leiming He, Li Wang, Fulong Zhang, Qinqin Wang, Lin Zhou   +7 more
semanticscholar   +1 more source

Physcion 1-glycosyl rhamnoside from seeds of Desmodium pulchellum

Phytochemistry, 1971
Abstract A new glycoside, the 1-glucosylrhamnoside of physcion has been identified in the seeds of Desmodium pulchellum (L).
R.D. Tiwari, R.K. Bansal
openaire   +1 more source

Inhibitory effects and mechanisms of physcion against Penicillium choerospondiatis, a serious pathogen in Phyllanthus emblica fruits.

Pesticide Biochemistry and Physiology
Emblica blue mold, a fungal disease caused by Penicillium choerospondiatis, poses a major threat to the industry of Phyllanthus emblica. Currently, resistance to chemical fungicides has been a challenge to its effectiveness on this disease. To explore an
Duo Lai, Delin Wang, Jian Qin, Qingli Zhuang, Xuehua Shao, Wei Xiao   +5 more
semanticscholar   +1 more source

Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.

International Immunopharmacology, 2020
Physcion 8-O-β-glucopyranoside (PSG), an anthraquinone extracted from Rumex japonicus Houtt, has various pharmacological effects, however, the effect of PSG on liver fibrosis and its related mechanism remain to be determined.
Chang Chen, Jingya Gu, Jue Wang, Yuehua Wu, A. Yang, Tingting Chen, Tingting Zhou, Zhaoguo Liu   +7 more
semanticscholar   +1 more source

Physcion 8-O-β-glucopyranoside induced ferroptosis via regulating miR-103a-3p/GLS2 axis in gastric cancer.

Life Science, 2019
AIM Gastric cancer (GC) is a common human malignancy tumor of digestive tract in worldwide. Physcion 8-O-β-glucopyranoside (PG) exhibits anti-tumor effects in various cancer cells.
Ying Niu, Jinping Zhang, Yalin Tong, Jiansheng Li, Bingrong Liu   +4 more
semanticscholar   +1 more source

Physcion Alleviates Osteoporotic Bone Loss by Inhibiting Osteoclast Formation and Promoting Osteoblast Differentiation.

Current pharmaceutical design
BACKGROUND Osteoporosis is a prevalent bone disorder resulting from imbalanced bone remodeling, characterized by excessive bone resorption and insufficient bone formation.
Jing Fan, Yaqian Hu, Jinhua Yin, Chu Gao, Chengxiang Zhao, Chao Zheng, Liu Yang, Weiguang Lu   +7 more
semanticscholar   +1 more source

RETRACTED: Physcion induces mitochondria-driven apoptosis in colorectal cancer cells via downregulating EMMPRIN

European Journal of Pharmacology, 2015
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief and the authors as panels from Figure 3D appear similar to panels from Figure 3C of article published by Zhi Wang, Hong Zhang,
Xuehong, Chen, Hui, Gao, Yantao, Han, Junli, Ye, Jing, Xie, Chunbo, Wang   +5 more
openaire   +2 more sources

Physcion, a tetra-substituted 9,10-anthraquinone, prevents homocysteine-induced endothelial dysfunction by activating Ca2+- and Akt-eNOS-NO signaling pathways.

Phytomedicine, 2020
BACKGROUND Homocysteine (Hcy) induced vascular endothelial dysfunction is known to be closely associated with oxidative stress and impaired NO system. 1,8-Dihydroxy-3-methoxy-6-methylanthracene-9,10-dione (physcion) has been known to has antioxidative ...
X. Ji, Hang Lyu, G. Zhou, Bo Wu, Yuan Zhu, T. Wu, Feng Zhang, S. Jin, K. Cho, J. Wen   +9 more
semanticscholar   +1 more source