Results 91 to 100 of about 1,189,976 (269)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

The Relationship between in Health Gymnastics Participation and Social Integration: A Comparative Study among Secondary School

Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae
This study aims to conduct a comparative investigation of the level of social integration between gymnastics practitioners and non-practitioners among secondary school students in the Wilaya of Guelma, Algeria.
Abdelmalek BOUFRIDA, Cherabcha RAFIKA, Seraiaia JAMEL   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The effect of Ramadan fasting on sleep quality, total sleep time, and daytime sleepiness in soccer players.

مجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية
This study aimed to examine the effect of Ramadan fasting on sleep quality, total sleep time, and daytime sleepiness in soccer players. Twenty-four U15 Algerian amateur soccer players voluntarily participated in this descriptive study (age = 14.25 ± 0 ...
Amar MOUISSA, Aissa SLIMANI
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Impact of the level of physical activities on emotional exhaustion, depersonalization, lack of personal accomplishment and burnout among students in the city province of Kinshasa

Turkish Journal of Kinesiology
The impact of the practice of physical activities on burnout and its dimensions remains very little documented among students living in subaerial African countries.
Liny Enyuka Kila, Constant Nkıama, Dalmond Kambale Mutsopi, Siloé Ntumba Tshiyamba, Carel Busano Nduakulu, Godefroid Kusuayi Mabele   +5 more
doaj   +1 more source

Physical activity and obesity

Biomedicine & Pharmacotherapy, 1994
Obesity is a major public health problem. Secular increases in the prevalence of obesity appear to be paralleled by decreases in physical activity. Although physical activity and weight are associated, the exact nature of the relationship remains uncertain.
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source