Results 51 to 60 of about 1,189,976 (269)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The effect of 12-week long exercise intervention, and 2-weeks of detraining period on lower limbs strength parameters and postural stability in older adults: a linear mixed model analysis

BMC Geriatrics
Background Muscle strength and postural control are essential components for performing daily living activities, particularly in older adults, and can therefore serve as screening tools for assessing fall risk in this population.
Lenka Svobodová, Martin Sebera, Tomáš Vodička, Aneta Svobodová, Andrea Horáková, Nikola Stračárová, Šarlota Svobodová, Veronika Eclerová, Tomáš Vespalec, Mario Kasović, Ana Carolina Paludo, Julie Bienertova-Vasku, Marta Gimunová   +12 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The effect of spaceflight and simulated microgravity exposure on thermoregulation in humans: a systematic review

npj Microgravity
Even a minor increase in core body temperature (CBT) raises physiological challenges in astronauts, leading to a decline in physical and cognitive performance.
Marta Gimunová, Michaela Beníčková, Adam Wagner, Jan Kučera, Julie Bienertova-Vasku   +4 more
doaj   +1 more source

The relative importance of morphological, physical and skill requirements for selecting talented U13 football players

Sport TK
Article accepted. The article will be published here soon. Pending final quality checks.
Dif Haroune, Ben Goua Ali, Seddaoui Chachou   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Impact Of Physical Activity On Some Physical, Physiological And Psychological Variables From The Point Of View Of Women With Type 2 Diabetes Who Engage In Physical Activity.

مجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية
The current research aims to identify the impact of physical activity on some physical, physiological, psychological variables from the point of view of women with type 2 diabetes who engage in physical activity in the sports halls in the city of Djelfa.
Benlarbi Oumkaltoum, Abdelkader belkheir
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Role Of The Teacher Of Physical And Sports Education In Establishing Health And Posturalawareness Of Middle School Pupils -a Field Study In The State Of M’sila -

مجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية, 2020
The current study aims atidentifying the role of teachers of physical and sports education in developing postural awareness among middle school pupils by evaluating teachers and their role in pupils’ postural awareness from one side and the contribution
Aissam Latreche, Sid Ali Benabderrahmane
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source