Results 141 to 150 of about 5,913,205 (362)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Card games are effective tools to enhance foundation year health and safety inductions
FEBS Open Bio, EarlyView.A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq +4 more
wiley +1 more source
Using Theory to Develop Healthy Choices in Motion, a Comprehensive, Experiential Physical Activity Curriculum. [PDF]
, 2019 Background: Research has shown that engaging in regular physical activity supports physiologic, metabolic, and immunologic processes, as well as quality of life. However, few youth in the United States meet the U.S.
Bergman, Jacqueline J +9 more
core
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source
Physical Activity Health Communication for Adults with Mood Disorders in the United States [PDF]
, 2019 Using national representative data, this study sought to examine receipt of physical activity communication and counseling among adults with mood disorders in comparison to the general population in the United States.
Keller, Abiola O., Ortiz, Angela
core +1 more source
Biomedicine & Pharmacotherapy, 1994 Obesity is a major public health problem. Secular increases in the prevalence of obesity appear to be paralleled by decreases in physical activity. Although physical activity and weight are associated, the exact nature of the relationship remains uncertain.
openaire +3 more sources
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay +12 more
wiley +1 more source
Sport as a privilege in Spain [PDF]
, 2010 The reduction of Physical Education hours in the Spanish curriculum originates from a false premise: families are already aware of the importance of physical activity, and attempt to compensate for the lack of it at school with an extra schedule.
Luis-Pascual, J-C, Manley, AJ
core
Interventions for promoting physical activity (review) [PDF]
Background Little is known about the effectiveness of strategies to enable people to achieve and maintain recommended levels of physical activity. Objectives To assess the effectiveness of interventions designed to promote physical activity in adults ...
Foster, C. +2 more
core +1 more source