Results 61 to 70 of about 6,226,403 (313)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Scientific Reports, 2022 Lifestyle risk behaviours such as smoking, physical inactivity, and unhealthy diet account for a considerable disease burden globally. These risk behaviours tend to cluster within an individual, which could have detrimental health effects. In this study,
Teketo Kassaw Tegegne +2 more
doaj +1 more source
Adolescent Physical Education and Physical Activity in California [PDF]
, 2011 Based on 2007 California Health Interview Survey data, examines participation in physical education and other physical activity among adolescents ages 12 to 17 by gender and county, and implications for health outcomes.
Allison L. Diamant +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Applying a technology‐based system for weight loss in adults with obesity
Obesity Science & Practice, 2016 Summary Objective The aim of this study was to compare an in‐person, group‐based behavioral weight loss intervention to technology‐based interventions in adults with obesity.
R. J. Rogers +7 more
doaj +1 more source
Associations among neighborhood socioeconomic deprivation, physical activity facilities, and physical activity in youth during the transition from childhood to adolescence [PDF]
, 2019 BACKGROUND: This study aims to examine the longitudinal association of neighborhood socioeconomic deprivation (SED) with physical activity in youth during the transition from elementary to middle school, and to determine if access to physical activity ...
Clennin, Morgan N +5 more
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Increasing Physical Activity Through Recess [PDF]
, 2012 Summarizes research on the effects of recess, including its benefits as an effective and efficient way to increase the amount of physical activity and enhance academic performance and trends in daily recess by school location and student ...
core
Differences in long- and short-term memory performance and brain matter integrity in seniors with different physical activity experience [PDF]
, 2019 Due to increasing changes in demographics, maintaining cognitive functioning later in life has become both economic and social concerns, and thus finding a cost-effective solution is one of the priorities in research.
Alruwais, Nourah +11 more
core +2 more sources