Results 111 to 120 of about 8,160,201 (307)

Quantification of the liquid window of deep eutectic solvents [PDF]

, 2018
Deep eutectic solvents (DESs) have been considered as a new class of green solvents with tunable physical properties based on the selective combination of their individual components.
Vis, Mark, Physical and Colloid Chemistry, van den Bruinhorst, Adriaan, Sub Physical and Colloid Chemistry, Esteves, A. Catarina C., Tuinier, Remco, Kollau, Laura J.B.M.   +6 more
core   +3 more sources

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Evolution of equilibrium pickering emulsions: a matter of time scales [PDF]

, 2010
A new class of equilibrium solid-stabilized oil-in-water emulsions harbors a competition of two processes on disparate time scales that affect the equilibrium droplet size in opposing ways.
Physical and Colloid Chemistry, Luigjes, B., Julius W. J. de Folter, Albert P. Philipse, Sub Algemeen Scheikunde, Daniela J. Kraft, Willem K. Kegel, Kraft, D.J., de Folter, J.W.J., Philipse, A.P., Kegel, W.K., Bob Luigjes, Sub Physical and Colloid Chemistry   +12 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

GENERAL AND PHYSICAL CHEMISTRY.

Journal of the American Chemical Society, 1899
n ...
openaire   +3 more sources

Professor Shin Sato, a Physical Chemist and Teacher for 50 Years

Substantia
This article presents a portrait of the scientific work of the Japanese physical chemist Shin Sato1 (1928-2022) at Tokyo Institute of Technology from the mid-1950s until 2019. His work included studies in both photochemistry and radiation chemistry with
Yona Siderer
doaj   +1 more source

Structural instability of shell-like assemblies of a keplerate-type polyoxometalate induced by ionic strength [PDF]

, 2009
We demonstrate a new structural instability of shell-like assemblies of polyoxometalates. Besides the colloidal instability, that is, the formation of aggregates that consist of many single layered POM-shells, these systems also display an instability on
Physical and Colloid Chemistry, Veen, S.J., Kegel, W.K., Sub Physical and Colloid Chemistry   +3 more
core  

Clay goes patchy [PDF]

, 2011
Empty liquids and equilibrium gels have so far been only theoretical possibilities, predicted for colloids with patchy interactions.
Physical and Colloid Chemistry, Kegel, W.K., Lekkerkerker, H.N.W., Sub Algemeen Scheikunde, Sub Physical and Colloid Chemistry   +4 more
core   +1 more source