Results 31 to 40 of about 480,626 (261)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Effects of Nano-Sized Al on the Combustion Performance of Fuel Rich Solid Rocket Propellants

Eurasian Chemico-Technological Journal, 2016
Several industrial- and research – type fuel rich solid rocket propellants containing nano-metric aluminum metal particles, featuring the same nominal composition, were prepared and experimentally analyzed. The effects of nano-sized aluminum (nAl) on the
W.Q. Pang, F. Q. Zhao, L. T. DeLuca, C. Kappenstein, H. X. Xu, X. Z. Fan   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Cálculo do Volume Molar de um Gás de van der Waals em SCILAB: o Método Newton-Raphson na Resolução de um Problema Físico-Químico

Orbital: The Electronic Journal of Chemistry, 2014
The use of software in chemical calculations is a constant reality in both laboratories as well as in simulation processes of chemical transformations.
Diogenes Filho, Antonio Alves de Melo Filho   +1 more
doaj   +1 more source

Dewatering Green Sapwood Using Carbon Dioxide Undergoing Cyclical Phase Change between Supercritical Fluid and Gas

Molecules, 2020
Conventional kiln drying of wood operates by the evaporation of water at elevated temperature. In the initial stage of drying, mobile water in the wood cell lumen evaporates.
Robert A. Franich, Roger Meder, Volker C. Behr   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Potensi Ekstrak Kulit Buah Manggis sebagai Inhibitor Korosi Baja Karbon dalam Larutan NaCl 1% Jenuh Karbon Dioksida

Αl-Kimiya: Jurnal Ilmu Kimia dan Terapan, 2019
Pemanfaatan limbah bahan alam sebagai inhibitor korosi belum banyak dilaporkan. Diantaranya adalah kulit buah manggis (Garcinia mangostana L.) yang dalam bentuk ekstraknya mengandung senyawa golongan flavonoid, alkaloid, dan tanin.
Tety Sudiarti, Nia Anriyani, Asep Supriadin   +2 more
doaj   +1 more source

Quantum chemical exercise linking computational chemistry to general chemistry topics

Chemistry Teacher International, 2020
Students in a second semester general chemistry course used quantum chemical calculations to investigate and reinforce general chemistry concepts. Students explored the isomers of hypochlorous acid, made predictions of miscibility via dipole moments ...
Simpson Scott, Evanoski-Cole Ashley, Gast Kellie, Wedvik Madeleine C., Schneider Patrick W., Klingensmith Isaac   +5 more
doaj   +1 more source