Results 81 to 90 of about 554,251 (307)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
TUDOR LUPAŞCU – A BRILLIANT SCIENTIST AND SKILFULL MANAGER [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2010 The Moldovan chemical community has recently honoured Professor Tudor LUPAŞCU on the occasion of his 60’s anniversary. Known as brilliant scientist and skilful manager, Professor LUPASCU is now the director of the Institute of Chemistry and one of the ...
Gheorghe Duca
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2002 Intended for the year long, calculus-based physical chemistry course for science and engineering majors, PHYSICAL CHEMISTRY follows a traditional organization while concentrating on core topics.
Ball, David W.
core
PRACTICAL PHYSICAL CHEMISTRY. [PDF]
Journal of the American Chemical Society, 1907 n ...
openaire +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Advances in Teaching Physical Chemistry
, 2007 This book brings together the latest perspectives and ideas on teaching modern physical chemistry. It includes perspectives from experienced and well-known physical chemists, a thorough review of the education literature pertaining to physical chemistry,
Ellison, Mark D. +3 more
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source