Results 101 to 110 of about 427,406 (314)

The effects of human disturbance on the activity of wild reindeer in different physical condition

Rangifer, 1988
<p>We compared two Norwegian wild reindeer herds, Knutsho in excellent physical condition and Hardangervidda in poor physical condition, before and during disturbance by human hunters in order to test whether physical condition effected foraging strategy under stress.
Skogland, Terje, Grøvan, Beate
openaire   +4 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

What is a model, why people don't trust them, and why they should [PDF]

, 2020
It is easier to make one s way in the world if one has some sort of expectation of the world s future behaviour. Even when facing a very complex problem, we are rarely in a state of full ignorance: some expectations of system behaviour and the level of ...
Boschetti, Fabio, Bradbury, Roger, Fulton, Elizabeth, Symons, John   +3 more
core  

Selecting eco-friendly thermal systems for the "Vittoriale Degli Italiani" historic museum building [PDF]

, 2015
Thermal systems installed in museums should guarantee the maintenance of the optimal hygrothermal parameters ranges for the conservation of their collection materials.
ASTIASO GARCIA, Davide, Cumo, Fabrizio, Di Matteo, Umberto   +2 more
core   +3 more sources

Physical Activity and Human Comfort Correlation in an Urban Park in Hot and Humid Conditions

Procedia - Social and Behavioral Sciences, 2013
AbstractUrban parks offer the ideal location and opportunities for physical activities to improve human psychological wellbeing. This study investigates the people's perception of their physical activities at the Shah Alam Lake Garden, Malaysia under hot and humid microclimate conditions.
Nasir, Rabiatul Adawiyah, Ahmad, Sabarinah Sh, Ahmed, Azni Zain   +2 more
openaire   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Sensory sensitivity as a link between concussive traumatic brain injury and PTSD. [PDF]

, 2019
Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma.
Fanselow, Michael S, Giza, Christopher C, Hoffman, Ann N, Hovda, David A, Lam, Jamie   +4 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Correlational analysis between joint-level kinetics of countermovement jumps and weightlifting derivatives [PDF]

, 2019
The purpose of this study was to investigate the mechanical similarity between net joint moments (NJM) of the countermovement jump (CMJ) and the hang power clean (HPC) and jump shrug (JS).
Comfort, P, Kipp, K, Suchomel, TJ
core   +2 more sources

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source