Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Combining training of muscle strength and cardiorespiratory fitness within a training cycle could increase athletic performance more than single-mode training.
Martijn Gäbler +4 more
doaj +1 more source
Relationships between lower-body muscle structure and, lower-body strength, explosiveness and eccentric leg stiffness in adolescent athletes [PDF]
The purpose of the present study was to determine whether any relationships were present between lower-body muscle structure and, lower-body strength, variables measured during a counter-movement jump (CMJ) and squat jump (SJ), and eccentric leg ...
Farley, Oliver R +5 more
core +1 more source
A department of methodology can coordinate transdisciplinary sport science support [PDF]
In the current sporting landscape, it is not uncommon for professional sport teams and organizations to employ multidisciplinary sport science support teams.
Davids, Keith +6 more
core
Evaluative conditioning as a symbolic phenomenon: on the relation between evaluative conditioning, evaluative conditioning via instructions, and persuasion [PDF]
Evaluative conditioning (EC) is sometimes portrayed as a primitive way of changing attitudes that is fundamentally different from persuasion via arguments.
De Houwer, Jan, Hughes, Sean Joseph
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Effects of complex-contrast training on physical fitness in male field hockey athletes
Study aim: This study aimed to examine the effects of a six-week complex-contrast training (CCT) intervention on the physical fitness of male field hockey athletes.
Thapa Rohit K. +5 more
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An investigation into sleep patterns and the effect of time of day on performance in youth swimmers [PDF]
The purpose of this study was to investigate sleep patterns in competitive youth swimmers and to establish any time-of-day effect on physiological and psychological variables linked to swimming performance.
Glen, Jonathan, Grant, Marie Clare
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

